Study On The Influence Of Herbal Cake Moxibustion On Hemorheology In Patients With Hyperlipidemia

Objective: To observe the effect of drug-partitioned cake-moxibustion on blood lipids,hemorheology and homocysteine in patients with hyperlipidemia through clinical trials.To explore the mechanism of hyperlipidemia treated by cake-partitioned moxibustion and evaluate its clinical efficacy.,to provide experimental basis for clinical promotion of drug cake moxibustion.Methods: Sixty patients with hyperlipidemia were randomly divided into the herb-cake moxibustion group and the simvastatin group.Both groups were treated for lifestyle changes.The lipid-lowering Chinese herbal compound powder was used in the herb-cake moxibustion group to make the drug cake.Moxibustion at acupoints,30minutes/time,3 times/week,2 groups of acupoints((1):Juque?Tianshu(two)?Fenglong(two);(2):Xinshu(two)?Ganshu(two)?Pishu(two))alternating moxibustion every 2 weeks,4 weeks for a course of treatment,a total of 3 courses of treatment;simvastatin group was given oral simvastatin,20mg/q N,a total of 12 weeks,3 courses.Two groups were treated before treatment,after 3 courses of treatment(12 weeks),4weeks of follow-up(16 weeks),and 12 weeks of follow-up(24 weeks),abdominal blood was taken for blood lipid index detection(TC,TG),HDL,and LDL),blood rheological parameters(whole blood viscosity,plasma viscosity,and erythrocyte aggregation index for each shear rate)and homocysteine(Hcy)levels were measured and statistically processed.Results: 1.the herb-cake moxibustion group: Compared with before treatment,after 3 courses of treatment(12th week),there was a significant effect on blood lipid,blood rheology,and Hcy improvement(P<0.05);followed up for 4 weeks(16th)Week)There was still significant improvement in the above indicators,and there was a significant difference before treatment(P<0.05).There was no difference in serum lipids,blood rheology,and Hcy levels before and after treatment for 12 weeks(Week24)(P>0.05).2.Simvastatin group: Compared with before treatment,after 3 courses of treatment(12th week),except HDL improvement was not statistically significant(P>0.05),and other indicators were improved significantly(P<0.05);follow-up 4 Weeks(week 16)had no statistically significant improvement in each index(P>0.05);follow-up for 12weeks(week 24)did not differ from the baseline before treatment(P>0.05).3.Compared between the two groups,after 3 courses of treatment(12 weeks),simvastatin group had better ability to regulate TG than herb-cake moxibustion group(P<0.05);the cake-partitioned moxibustion group had better effect on improving HDL than Xin In the valstatin group(P<0.05),there was no difference in the ability of the two groups to control TG,LDL,hemorheology,and Hcy(P>0.05).4.Compared between the two groups,there was no significant difference in TG and simvastatin group(P>0.05),and the other indicators were significantly different from the simvastatin group in follow-up 4 weeks(16th week).(P<0.05).5.There was no difference in serum lipids,blood rheology,and Hcy between the two groups at follow-up of 12 weeks(24 weeks)(P>0.05).Conclusion:the herb-cake moxibustion and simvastatin have similar therapeutic effects on hyperlipidemia,and both have obvious regulation effect.Clinical popularization and application;The short-term curative effect of the herb-cake moxibustion group was significantly higher than that of the simvastatin group,but the long-term curative effect of the two treatment methods was not significant.