A Correlation Analysis Of Pathogens And Prognosis In Fungal Keratitis

Objective To investigate the pathogenic factors of pathogenic keratitis and the relationship between pathogens and pathogenic bacteria.Methods A total of 115 patients with fungal keratitis were enrolled in this study from June 2015 to June 2016.The patients were diagnosed by corneal scraper microscopy,fungal culture and drug treatment.The pathogenesis of the selected cases was evaluated,Pathogens,the time of treatment,the severity of the disease and the prognosis of the patients,and to analyze the correlation between the relevant indicators and the prognosis of the patients.RESULTS: A total of 115 patients with fungal keratitis were enrolled in this study.Pathological factors included 76 cases of ocular trauma,accounting for 66.0%.The long-term abuse of antibiotics or hormones was 22 cases(19.1%).The effect of corneal contact was 6% Past ocular surface disease in 8 cases,accounting for 7.0;the other 3 cases,accounting for 2.6%;visible fungal keratitis is the main cause of eye trauma history.After 6 months of follow-up,the prognosis of patients was 93 cases(80.9%),12 cases(10.4%)had moderate prognosis and 10 cases(8.7%)had poor prognosis.The distribution of pathogens showed that the proportion of Fusarium was50.4%,followed by Aspergillus accounted for 22.6%,and the pathogen species were found to be significantly related to the prognosis of fungal keratitis.,The highest cure rate of grade ?,and the cure rate of the drug was prolonged with the prolongation of treatment time.Compared with the severity of the disease,the prognosis of patients with mild disease was better and the prognosis was worse with the condition.Conclusion The history of ocular trauma is a common cause of fungal keratitis in China.Fusarium,Alternaria and Aspergillus are the main pathogens of common fungal keratitis.Fusarium and Aspergillus pathogens strong,the resulting keratitis drug treatment effect is poor,long cycle,poor visual acuity,high rate of surgery;Alternaria alternata and other bacteria are relatively weak pathogenicity,the resulting The prognosis of keratitis is relatively good;and the patient's treatment time,the severity of the disease and its prognosis was significantly correlated.