| Purpose1.To explore the effect of abdominal compression on changing of active standing blood pressure in patients with orthostatic hypotention in Parkinson's disease.2.To find The difference of abdominal compression in ? BP(?systolic blood pressure/ ? diastolic blood pressure)in active standing and the influence on patients' comfort as well as the characteristics distribution of positive patients under the condition,in order to find out the suitable one.3.To determine the clinical characteristics of patients with improved blood pressure therefore to find a evidence for clinical popularize.Methodwe selected consecutive eligible patients from January to December 2017.All subjects estimated by neurologists attributable to the affiliated Hospital of Soochou University,department of Neurology.All the 76 patients which have been diagnosed with Parkinson disease combined with orthostatic hypotension,according to active standing test for two times.Protocol evaluated in moving from supine to standing both with 20 mm Hg and 40 mm Hg abdominal compression with inflatable binder in place.The primary outcome variable included ?BP(?SBP/?DBP)in postural changes during the different time.Secondary outcome variables included subject comfort assessments while the compression was given.Result :1.Analysis of general data of 76 PD patients with OH shows that 62.0%(47)males;43.0%(29)females,mean age 68.5±7.5;with 52.6%(34)combined with hypertension,1.3%(1)combined with diabetes mellitus;and 1.3%(1)both combined with hypertension and diabetes mellitus;for 11.8%(9)had no medicine used,and 14.5%(11)treat with one kind of medicine;and 34.2%(26)treat with two kinds of medicine;and 39.5%(30)treat with more than three kinds of medicine;with 35.5%(27)are symptomatic;mean height(?)163.7±6.2;mean weight(Kg)61.0±7.0;mean body mass index 22.7±2.6;mean abdominal circumference(?)89.1±8.3;with19.7%(15)had no education experiences and 25%(19)with elementary education;35.5%(27)with senior education;19.8%(12 ?)with high school education.2.compared with ?BP(?SBP/?DBP)from supine to standing in the moment of 15 sec and 3min after standing position,20 mm Hg abdominal compression has a significant difference with non-intervention,both P < 0.00;compared with ?BP(?SBP/?DBP)from supine to standing in the moment of 15 sec and 3min after standing position.40 mm Hg abdominal compression has a significant difference with non-intervention,(P < 0.00);3.Compared with different time(15sec VS3min)after standing position,?SBP of two levels of abdominal compressions both have significant differences,(P<0.05);3.There were no significant differences in? BP(?SBP/?DBP)between two levels of interventions;(P>0.00),but the comfort evaluation has a significant difference,(P < 0.00);4.The general data of patients with blood pressure changed prominently under 20 mm Hg were analyzed,the result shows the height was statistically significant.(P<0.05);Conclusion :1.Using abdominal compression before standing can prevent orthostatic hypotension in patients with Parkinson's disease;the impact of changes of systolic blood pressure is more extrusive than diastolic blood pressure;2.The two levels of abdominal compression showed same effort,however,people are more comfortabal with 20 mm Hg abdominal compression than 40 mm Hg..3.Patient's height with less than 165 cm are in good reactive under 20 mm Hg abdominal compression. |
PDF Full Text Request