Mitral regurgitation(MR)is the second most common clinically relevant valvular heart disease in adults,with an incidence of about 2% to 3% per year.Surgery,either replacement or repair,has been the mainstay of therapy for primary MR,but In high-risk or inoperable patients,surgery was limited.under this circumstance,alternative a new minimally invasiv therapy has been introduced and has proven to be safe and effective in patients with MR.Edge-to-edge repair with the MitraClip system is applied worldwide for primary and secondary,high-risk and low-risk patients of MR.At present,as long as the valve anatomyis suitable,MitraClip is available.Because MitraClip is a new treatment,the long-term prognosis and indicationneed to be explored by more clinic trials. |