Influence On The Incidence And Degree Of Radiation Pneumonia In Patients With Esophageal Cancer By Leihuo Moxibustion Therapy

Objective:The research collect and analyze esophageal cancer patients given radiation therapy in Tumor Hospital of Jiangsu Province from April 2015 to February 2016.Observ the quality of life improved,TGF-?1 changes to analyze the influence of incidence and occurrence degree of radiation pneumonia in patients with esophageal cancer treated by Leihuo moxibustion.The objective is seeking a secure,effective therapy to alleviate radiation-induced lung injury induced by thoracic radiotherapy in patients with esophageal carcinoma.Methods:Divide meet the inclusion criteria of patients with non randomized into treatment group(Leihuo moxibustion radiotherapy group)20 cases,the control group(conventional therapy group)20 cases.Two groups were treated with basic treatment:conventional radiotherapy(6-7 weeks for 1 courses,the total radiation dose per course for 45-66Gy).The control group received only basic treatment.The treatment group of Leihuo moxibustion treatment in the conventional radiation therapy on the basis of 1 times a day,5 times a week,from the beginning of the end of the day to radiotherapy in patients with radiotherapy 1 day course of treatment for 1 courses;within 6 months of treatment,synchronized with radiotherapy,6 months until the end of the observation period were observed and recorded.Observe and record the TGF-?3 1,RTOG grade and QOL score.All data were analyzed by SPSS22.0 statistical software.Results:Comparison between two groups,the incidences of radiation pneumonitis were no statistically significant difference at the end of radiotherapy;After 3 months,the incidence of radiation pneumonitis of treatment group was lower than that of the control group,and the difference was statistically significant;the difference between two groups at the end of radiotherapy and radiotherapy after 3 months of radiation pneumonitis occurrence degree of the difference was not significant.TGF-beta 1 was no significant difference at the end of radiotherapy between the two groups;After 3 months,TGF-?1 of treatment group was significantly lower than the control group,the difference was statistically significant.The QOL score of treatment group at the end of radiotherapy and 3 months after radiotherapy were higher than the control group,the difference was statistically significant.The appetite,fatigue and sleep score of the treatment group were higher than the control group at each stage,the difference was statistically significant.Conclusion:1.Leihuo moxibustion can reduce the incidence of radiation pneumonia in patients with esophageal cancer and have a tendency to reduce the incidence of radiation pneumonia..2.Leihuo moxibustion may reduce the occurrence of radiation pneumonia by inhibiting the expression of TGF-?1;3.Leihuo moxibustion can improve the quality of life of patients with esophageal cancer and effectively improve the appetite,fatigue and sleep status of the patients.