Pathological Analysis Of Risk Factors To Induce Diabetes Foot

BackgroundIn recent years,along with the people's diet structure,work and rest habits change,the incidence of diabetes increased year by year,the control effect of its mortality and morbidity is still insufficient ideal.Diabetic foot,the more common complications of diabetes,with protracted,disability rate higher characteristic,the serious ones can be deadly.The domestic and foreign data display,1/3 of the diabetic patients' medical costs for whole life directly or indirectly on the prevention and treatment on diabetic foot.Thus,the medical economic burden that diabetes foot brings has become a social wide problem.In order to improve the control effect of diabetic foot,pathologic risk factors of diabetic foot are important to clear.ObjectiveTo investigate the risk factors of diabetic foot disease,and provide clinical reference for the prevention and treatment of diabetic foot.Methods(1)184 cases of diabetic foot patients as the research object,analysed its clinical diagnosis and treatment of data,statistical analysis of age,the incidence of diabetic foot disease course and pathologic gradingetc..(2)184 cases of diabetic foot as the study group,and in 150 patients with diabetes and non diabetes foot as the control group,the biochemical indexes of the contrast between the two groups and general information.Methods: 184 patients with diabetic foot according to the relatedstandard,will be divided into neurogenic,mixed and ischemic diabetic foot,biochemical index contrast between the three groups and general information.184 patients were divided into mild and severe diabetic foot,biochemical indexes and pathological relationship of contrast between the two groups.Then use the multi factor regression analysis,find out the risk factors of diabetic foot.Results(1)Diabetic patients over 50 years old is high risk,and the disease course in general more than 5 years,the main complication forretinopathy,peripheral neuropathy,diabetic nephropathy.Diabetic foot ulcers are mainly distributed in the toe position,the inducement with hot water burns and scald / shoes do not fit these two factors are common.(2)Compared to the diabetic foot and non diabetic foot patients,there issignificant difference in age,arteriosclerosis,carotid atherosclerosisindexes such as WBC,Hcy,numerical and PCT were increased,ALB,HCT and TC were significantly decreased,and the difference between groups was statistically significant(P<0.05).Multiple regression analysis showed,HbA1 c,Hcy and WBC are independent risk factors of diabetic foot lead(P<0.05).(3)Nerve,mixed and coronary heart disease,ischemic diabetic foot in patients with hypertension and cerebral infarction and other basicdiseases had statistically significant difference between the rate(P<0.05).The comparison results of biochemical indicators show,threegroups of patients with Hcy levels had statistical difference(P<0.05),the other no statistical difference(P>0.05).Multiple regression analysis showed,Hcy is the independent risk factors of ischemic diabetic foot.(4)A mild diabetic foot and severe baseline data of patients with diabetic foot and no statistical difference(P>0.05).Statistically significant difference between the two groups of patients with ALB,HDL-C,WBC,PCT index(P<0.05).The results of regression analysis showed that,WBC level is a risk factor for severe diabetic foot.ConclusionsDiabetes duration of more than 5 years to patients and over 50 years of age as a high-risk group,ulcer site is mainly distributed in the toe,foot dorsal and plantar parts,cerebral infarction,diabetic nephropathy,hypertension is more common complications.HbA1 c,Hcy and WBC levels of diabetic foot high is the result of independent risk factors,the increase of WBC is an independent risk factor of causing severe diabetic foot.Hcy is the result of an independent risk factor for ischemic diabetic foot.