The Clinical Observation Of BuShen Expelling Wind Activating Blood And Hemostasis Decoction On The Treatment Of HSPN(Qi-Yin Deficiency Syndrome)

Objective: To investigate the efficacy and safety of bushen expelling wind and activating blood and hemostasis in the treatment of Henoch Schonlein nephritis(Qi-Yin deficiency syndrome)by bushen expelling wind and promoting blood circulation and hemostasis.To analyze the etiology and pathogenesis of Henoch Schonlein purpura,and to illustrate the establishment and analysis of the method of bushen expelling wind promoting blood circulation and hemostasis.The feasibility of this method in the treatment of purpura nephritis is explained theoretically and experimentally,so as to provide an effective method for purpura nephritis.Methods: According to the inclusion criteria and exclusion criteria of this experiment,it is in line with the diagnostic criteria of Chinese medicine and Western medicine for Henoch Schonlein purpura nephritis.The patients who met the criteria were randomly divided into the experimental group(Chinese medicine + basic treatment)and the control group(nephritis rehabilitation tablet + basic treatment).A total of 60 patients were observed in February.Two groups of patients before and after treatment were observed before and after treatment.According to the data obtained,the preliminary treatment effect and safety evaluation were made after the statistical treatment.Results: The total effective rate of the two groups was compared,the total effective rate of the experimental group was 87%,the total effective rate of the control group was83%,The difference between the two groups was not statistically significant(P >0.05),and there was no difference between the two groups of Western medicine.The two groups improved the curative effect of TCM symptoms.The two groups of TCM symptom scores decreased compared with those before treatment.The two groups could improve the HSP distribution,HSP color and HSP morphology.There was a significant difference between the two groups after treatment(P<0.05).The difference between the two groups was statistically significant,and the efficacy of the experimental group was better than that of the control group.The two group in thetreatment of hand and foot fever,tinnitus and the sore lumbus and knees,oropharyngeal dry,constipation integral comparison(P < 0.05),treatment group than the experimental group.The two groups of abdominal pain,joint pain,less energy and weakness of TCM syndrome score(P > 0.05),no statistical significance,the two groups in improving abdominal pain,joint pain,less energy and fatigue were not significantly different.The two groups in the improvement of 24 h urine protein(P >0.05),No difference between the two groups.The two groups in the improvement of urine red blood cells(P < 0.05),the difference between groups was statistically significant,but the experimental group was better than the control group.Safety observation,there was no significant difference between ALT and AST(P>0.05),urea nitrogen and serum creatinine between the two groups after treatment,indicating that there was no significant difference in safety index between the two groups.Conclusion: bushen expelling wind activating blood and hemostasis and nephritis rehabilitation tablets combined with basic treatment can improve TCM symptoms of allergic purpura nephritis,reduce 24 h urinary protein,microalbuminuria and urine red blood cells.But the effect of invigorating the kidney and removing wind and promoting blood circulation to hemostasis is better than that of nephritis.It is feasible and safe to treat anaphylactoid purpura nephritis(Qi Yin two deficiency syndrome)by Invigorating the bushen expelling wind and promoting blood circulation to hemostasis.