Investigation Of The Relationship Between Sleep Disorders And Functional Gastrointestinal Disorders

Objectives: To investigate the relationship between sleep disorders and the incidence of functional gastrointestinal disorders(FGIDs)by providing questionnaires to nurses and inpatients in the digestive department of a top-level hospital in Xi'an,and provide evidence for the treatment of FGIDs.Methods: The study was divided into two parts.The first part of the experiment was to analyze the incidence of sleep disorders in 419 inpatients in the Department of Gastroenterology using the Pittsburgh Sleep Quality Scale(PSQI);the second part of the experiment divided 231 hospital nurses into shifts and shifts.Nurses were trained to use the Rome IV diagnostic questionnaire for functional gastrointestinal disorders,PSQI questionnaire,social time difference scale,SAS,SDS,and the Chinese version of the Stress Perception Scale(CPSS)investigated two groups of nurses and analyzed the association between sleep disorders and other psychosocial factors and the incidence of FGIDs.Result: Part I: Investigation of Sleep Disorders in Inpatients of Department of Gastroenterology1.General investigation of inpatientsA total of 419 inpatients in the Department of Gastroenterology were investigated,including 209 males and 210 females.The ratio of male to female was approximately 0.99:1,and the age ranged from 24-88(average 61.04±14.22 years).In the same period,44 healthy persons without gastrointestinal function and organic lesions were selected as controls.There were 24 males and 20 females,with a male to female ratio of 1.2:1 and an age of 26-85 years(mean 56.05±17.80 years).There was no significant difference in the age and gender of inpatients and healthy controls.2.Disease profile of inpatients in Department of GastroenterologyOf the 419 inpatients,69(16.47%)were FGIDs,43(10.26%)were biliary and pancreatic diseases,42(10.02%)were peptic ulcers,46(10.98%)were digestive tract tumors,and the stomach colon was There were 77 polyps(18.38%),gastroesophageal reflux disease(GERD)in 30 cases(7.16%),decompensated cirrhosis in 51 cases(12.17%),and other intestinal diseases in 61 cases(14.56%).Gastrointestinal polyps accounted for the highest proportion of hospitalized patients(18.38%),and GERD patients accounted for the lowest proportion of inpatients(7.16%).3.Comparison of prevalence of sleep disorders in inpatients in the Department of GastroenterologyAmong 69 cases of FGIDs,the prevalence of sleep disorders was 81.16%;in 43 cases of biliary and pancreatic diseases,the prevalence of sleep disorders was 44.19%;in 42 cases of PU patients,the prevalence of sleep disorders was 61.90%;46 cases were digested In patients with tumors,the prevalence of sleep disorders was 82.60%;in 77 patients with colonic polyps,the prevalence of sleep disorders was 62.34%;in 30 patients with GERD,the prevalence of sleep disorders was 66.67%;51 patients with cirrhosis In the decompensated patients,the prevalence of sleep disorders was 72.55%;in the other 61 patients,the prevalence of sleep disorders was 67.21%.Among 44 healthy controls,the prevalence of sleep disorders was 31.82%.Except for biliary and pancreatic diseases,the prevalence of sleep disorders in hospitalized patients with gastroenterology was significantly higher than that in healthy controls,with a significant difference(P<0.01).4.Comparison of scores of PSQI questionnaire components between patients with digestive tract cancer and healthy controlsIn this study,the prevalence of sleep disorders in patients with digestive tract tumors was higher than those in other digestive system diseases(P<0.05).The PSQI components were analyzed to find the quality of sleep,sleep time,sleep time,sleep efficiency,sleep disorders,Scores of components such as daytime dysfunction and scores of PSQI were significantly higher than those of healthy controls(P<0.01).5.Comparison of scores of PSQI questionnaire components between FGIDs patients and healthy controlsIn this study,the prevalence of sleep disorders in patients with FGIDs was second only to patients with digestive tract tumors and higher than those in other digestive system diseases(P<0.05).The PSQI components were analyzed to find the quality of sleep,sleep time,and sleep time,sleep efficiency,sleep disorders,Scores of components such as daytime dysfunction and scores of PSQI were significantly higher than those of healthy controls(P<0.01).Part II: The relationship between sleep disorder and the incidence of FGIDs in nurses1.The general condition of the nurseA total of 244 nurses participated in the survey,with 231 valid scales.Of the 231 nurses,105 were day-care nurses,aged 20-52 years old(average 28.71±5.50 years old),physical index(BMI)16-31.7(average 22.40±5.31),marital status unmarried 38 people(36.2%),already Marriage 67(63.8%),divorced 0(0%),widowed(0%),education below junior high school 0(0%),high school 3(2.9%),university 99(94.3%),graduate students 3 or more(2.9%);126 nurses with shifts,aged 20-47(average 27.93±3.36),BMI 15.7-32.1(average 21.37±2.62),unmarried 52(41.3%),married 73(57.9%),1 divorced(0.08%),0(0%)widowed,0(0%)below junior high school,5(4.0%)high school,and 119(94.4%)university 2 graduate students and above(1.6%).There was no difference in the age,BMI,marital status,and education status between the white class and shift nurses.2.The prevalence of nurse FGIDsOf the 231 nurses,32 were diagnosed with FGIDs and the prevalence rate was 13.8%.Among them,the prevalence of functional dyspepsia(FD)was 3.5%,the prevalence of functional constipation(FC)was 3.5%,the prevalence of irritable bowel syndrome(IBS)was 1.7%,and the prevalence of ball disease was At 1.2%,the prevalence of functional abdominal distension(FAB)was 0.09%,the prevalence of functional chest pain was 0.09%,the prevalence of non-specific functional bowel disease was 0.09%,and the prevalence of ruminant syndrome was 0.09%.The prevalence of dysphagia was 0.04%.3.The correlation between the general condition of nurses and the prevalence of FGIDsThe age,BMI,marital status,education level of nurses and the prevalence of FGIDs were not correlated(P>0.05).4.Comparison of the prevalence of FGIDs between nurses in shift classes and shiftsOf the 231 nurses,105 were white-shift nurses,the prevalence of FGIDs was 8.6%,126 were nurses in shifts,and the prevalence of FGIDs was 18.3%.The prevalence of FGIDs in shift nurses was significantly higher than that of nurses in white classes,and the difference was statistically significant(P<0.05).5.Comparison of sleep quality among nurses with white shift and shift nursesThe PSQI total score(9.68±4.60)of shift nurses was significantly higher than that of white nurses(6.22±3.58),and the difference was statistically significant(P<0.05).6.Comparison of other social psychological factors among nurses with white shift and shift nursesThe anxiety score,depression score,stress total score,and social time difference score(54.37±4.96,49.28±5.31,39.24±8.41,1.52±0.24)of shift nurses were significantly higher than those of white nurses(49.88±2.51,42.37±3.45,30.18 ± 8.55,1.03 ± 0.07),the difference was statistically significant(P<0.05).7.Comparison of sleep quality of shift nurses with FGIDs and without FGIDsThe total score of PSQI(10.67±3.41)in shift nurses with FGIDs was significantly higher than that of non-FGIDs(7.24±4.46).The difference was statistically significant(P<0.05).8.Comparison of other psychosocial factors of shift nurses with FGIDs and without FGIDsThe anxiety score,depression score,total stress score,and total social difference score(56.98±2.23,50.35±3.15,40.44±5.37,1.83±0.37)of nurses with FGIDs were significantly higher than those of non-FGIDs(52.37±4.46,47.28±2.29,34.18±6.49,1.35±0.21),the difference was statistically significant(P<0.05).9.Analysis of the correlation between FGIDs,sleep quality and psychosocial factors in shift nursesThe prevalence of FGIDs in shift nurses was significantly positively correlated with total PSQI scores,total scores of anxiety,depression,stress total scores,and total social time difference(P<0.05).10.Factors affecting the prevalence of FGIDs in nursesThe factors affecting the incidence of FGIDs in nurses were sleep disorder,anxiety,depression,social time difference,and stress.The standard regression coefficients were 0.491,0.589,0.213,0.262,and 0.712,respectively.Conclusions:1.In addition to patients suffering from biliary and pancreatic diseases,there were sleep disorders in other inpatients with gastroenterology,and the prevalence of sleep disorders was significantly higher than that of healthy controls.2.Among the hospitalized patients in the Department of Gastroenterology,the prevalence of sleep disorders was highest in digestive tract tumors and FGIDs,which was 82.60% and 81.16%,respectively,which was significantly higher than that of other hospitalized patients.3.The total prevalence of FGIDs in nurses surveyed in this study was 13.8%.The prevalence of FGIDs among shift nurses(18.3%)was significantly higher than that of white nurses(8.6%).4.The age,BMI,marital status,and educational level of nurses were not related to the incidence of FGIDs.5.The shift work has an adverse effect on the nurse's sleep and mental health.6.Socio-psychological factors such as sleep disorders,anxiety,depression,and social time differences are closely related to the incidence of FGIDs in shift nurses.