The Value Of Two-dimensional, Three-dimensional Ultrasound In The Diagnosis Of Benign And Malignant Breast Masses

Objective: This article aims to analyze the characteristics of two-dimensional and three-dimensional ultrasound images of benign and malignant breast masses,to compare the two-dimensional ultrasound with the combination of two-dimensional and three-dimensional ultrasound in the diagnostic efficacy of breast masses,and to explore the application value of two-dimensional ultrasound and three-dimensional ultrasound in breast tumors.Methods: 178 cases(218 tumors)found by clinical or ultrasonic examination were collected.Two-dimensional ultrasound was performed at first,and three-dimensional ultrasound was examined on this basis.All the masses were confirmed by pathology.The observation was performed in the differences between benign and malignant masses in two-dimensional ultrasound in terms of shape,orientation,edge,internal echo,calcification,posterior characteristics,blood flow and in three-dimensional ultrasound in terms of shape,edge,internal echo,calcification,convergence sign,halo sign,catheter change.The Logistic regression analysis was used to screen the predictive factors for the diagnosis of benign and malignant masses in two-dimensional and three-dimensional ultrasound images.Comparison was given in the diagnostic efficiency of two-dimensional ultrasound and the combination of two-dimensional and three-dimensional ultrasound in benign and malignant breast tumors regarding sensitivity,specificity,accuracy,Youden's index,positive predictive value and negative predictive value.Results: There were 150 benign masses and 68 malignant masses in the total(218)breast tumors.The characteristics of shape,orientation,edge,internal echo,calcification,posterior characteristics and blood flow in two-dimensional ultrasound images were significantly different between benign and malignant breast masses(P<0.05).Logistic regression showed that the risk factors for the diagnosis of breast malignant tumors include posterior shadow,irregular shape,rich blood flow and microcalcification.The relative risks(OR values)were 43.07,9.76,5.47,4.54 respectively.The characteristics of shape,internal echo,calcification,convergence sign,halo sign and catheter change in three-dimensional ultrasound images were significantly different between benign and malignant breast masses(P<0.05).Logistic regression showed that the risk factors for the diagnosis of breast malignant tumors involve halo sign,convergence sign,catheter change,irregular shape and inhomogeneity of internal echo.The OR values were 29.23,8.31,6.48,4.07,3.43 respectively.The differences between two-dimensional ultrasound and the combination of two-dimensional and three-dimensional ultrasound in the diagnosis of breast tumors were not significant in terms of sensitivity,specificity,accuracy,Youden's index,positive predictive value and negative predictive value.Conclusions: Two-dimensional ultrasound and three-dimensional ultrasound can be used to identify benign and malignant breast masses.In two-dimensional ultrasound,such factors as posterior shadow,irregular shape,rich blood flow and microcalcification are the main factors influencing the diagnosis of malignant breast masses.And in three-dimensional ultrasound,the factors including halo sign,convergence sign,catheter change are the main factors influencing the diagnosis of malignant breast masses.Two-dimensional ultrasound and the combination of two-dimensional and three-dimensional ultrasound have high diagnostic value in the diagnosis of breast tumors,and three-dimensional ultrasound can be used as a complementary method of two-dimensional ultrasound.