The Effect Of Depression And Anxiety On Prognosis Of Patients With Chronic Heart Failure

[Objective]135 patients with chronic heart failure(chronic heart failure,CHF)met the selected criteria were selected through prospective consecutive selection.Baseline information,electrocardiogram,imaging data,and biological samples were collected for selected patients,followed by the January follow-up after discharge,and the patient-centered clinical outcome events were collected during the follow-up period,ECG,imaging data and biological samples.The Depression and anxiety status were assessed with depression(PHQ-9)and anxiety(GAD-7)questionnaires,and the effects of depression and anxiety on the prognosis of patients with heart failure were observed,and the effects of different degrees of depression and anxiety on the prognosis of heart failure were evaluated.[Method]1.2016 years from December to January 2018,the heart failure was the main cause,patients in the Kunming Medical University and willing to participate in the follow-up investigation of patients with chronic heart failure as the object of study,access to patients and their families informed consent and signed into the group,and then establish a patient profile.2.Collect the patient baseline information,for the selected patients,within 48 hours of admission to complete all biological sample collection,according to the unified request to collect blood and urine samples.When the patient is in stable condition during 7-10 days of admission(if the hospitalization days are less than 7 days,complete before discharge),the patient's ECG,heart ultrasound and chest film are collected,and completed hospitalization information collection,including medical records information extraction,quality of life(EQ-5D),heart failure Quality of life(KCCQ-12)questionnaire survey.3.Complete the patient's depression(PHQ-9),anxiety(GAD-7)questionnaire before discharge,according to the general depression,anxiety questionnaire,the patients were divided into the group without emotional disorder,anxiety Group,depression Group,depression and anxiety in common disease Group.4.During the 1-month follow-up,the patient was asked to perform biological samples,ECG,ultrasound and imaging data collection,and the quality of life(EQ-5D)and quality of life(KCCQ-12)questionnaires were used to evaluate the patients 'lives.5.The study uses SPSS20.0 medical statistics software for statistical processing.K-s test method for normal test of metrological data,the data of continuous variables with normal distribution are compared with T test or variance analysis,using the mean + standard deviation,the non-normal distribution data are compared using Mann-whitney U rank and test,using(rank mean)median number,the counting data compare using the card square test,expressed in percentages.When the two variables obey the nornal distribution,the Pearson correlation analysis,the rank data or the double variable not obeying the normal distribution are adopted by the Spearman rank correlation,and the risk factors of affective disorder are analyzed by two logistic regression.All of the analyses were statistically significant with bilateral 95%confidence interval(p<0.05).[Results]1.The study included 135 cases,1 cases of hospitalization,2 cases died in hospital,3 cases of hospital follow-up,and normal selected patients were 129 cases,among them 81 cases,female 48 cases,average age 61.09 ± 13.67,129 cases of depression group of patients with heart failure in total 55 cases,42.6%of patients with heart failure in anxiety group,49 cases,accounting for 38%,no mood disorder group of heart failure in a total of 52 cases,accounting for 40.3%.2.In depressive groups,patients with heart failure with no mood disorder were in gender,there were statistically significant differences in NYHA grading,hospitalization days,fasting blood glucose,BNP,atrial fibrillation,6 minute walk,EQ5D,KCCQ score(p<0.05),and the number of patients with heart failure in anxiety group were in hospital days,NYHA grading.There were statistically significant differences in fasting blood glucose,creatinine,BNP,atrial fibrillation,LVEF,6-minute walk test,EQ5D,KCCQ score(p<0.05),and no statistically significant difference in the remaining indices.3.There were significant differences in EQ5D,KCCQ scores and number of readmission cases in patients with heart failure in the Depression group and anxiety group in January compared with those without mood disorder(p<0.05).4.Depression and anxiety had negative effects on EQ5D and.KCCQ scores during hospitalization and discharged January,the higher the score of depression and anxiety,the lower the EQ5D and.KCCQ scores.[Conclusion]The study,patients with chronic heart failure during hospitalization and 1 months of hospital discharge follow-up,concluded:1.In patients with chronic heart failure,there was a high incidence of anxiety and depression,which accounted for 42.6%and 38%of the proportion of patients,respectively.2.Depression and anxiety had negative effects on EQ5D and.KCCQ scores during hospitalization and discharged January,the higher the score of depression and anxiety,the lower the EQ5D and.KCCQ scores.3.The quality of life dimensions and total score of patients with chronic heart failure with anxiety and depression were lower than those with chronic heart failure without anxiety and depression.4.In patients with chronic heart failure,anxiety and depression can affect the prognosis of patients with chronic heart failure,the quality of life after discharge and discharge from the hospital after January,and the prognosis of patients with heart failure in depressive group and anxiety group is worse than those with chronic heart failure with anxiety and depression.