Clinical Characteristics Of Patients With Nonvalvular Atrial Fibrillation Combined With Smoking

Objective:To investigate the clinical characteristics of non-valvular atrial fibrillation(AF)patients with smoking,and the effect of smoking on atrial fibrillation.Methods:A total of1729 patients with non-valvular atrial fibrillation,who were admitted to our hospital from January 2010 to December 2016 were enrolled.According to the exclusion criteria,432 patients were excluded and the remaining 1297 patients.According to whether there was active smoking history,1297 patients with AF were divided into smoking group(n=452)and non-smoking group(n=845),The difference of general clinical data between two groups of patients with AF was analyzed.Logistic regression analysis was used to analyze whether smoking was an independent risk factor for non-paroxysmal atrial fibrillation.Results : The average age of the smoking group was significantly lower than that of non-smoking group,while the cardiomyopathy,body mass index,serum creatinine,IVST and LAD were higher than those in the non smoking group(P< 0.05).According to smoking index,the smoking patients were divided into mild group(n=269),moderate group(n=118)and severe group(n=65).The difference between the 3 groups in paroxysmal AF was statistically significant(52.4% vs 47.5% vs.35.4%,P<0.05).The difference of LAD in the 3 groups was statistically significant(39.07±6.26 mm vs.41.21±7.09 mm vs.44.60±6.04 mm,P<0.05).According to the different types of atrial fibrillation,The smoking index in persistent AF group was significantly higher than that in paroxysmal AF group(P<0.05).In the logistic regression analysis,smoking is an independent risk factor for non-paroxysmal AF(OR=1.407,95%CI:1.109-1.786,P=0.005).Conclusion : Atrial fibrillation combined with smoking in patients showed younger age and larger LAD,smoking is an independent risk factor for maintenance of atrial fibrillation.