The Application Value Of Blood Lipid Detection In Pulmonary Thromboembolism

Backgrounds:Pulmonary thromboembolism(pulmonary thromboembolism,PTE)as the main clinical type of pulmonary embolism(pulmonary embolism,PE)is one of the most common clinical symptoms with high mortality and disability.In recent years,with the improvement of various means of examination,the diagnosis and treatment of acute pulmonary embolism(APE)has made obvious progress.However,because of the lack of typical clinical manifestations of the disease and the relatively high requirements of imaging examination,it is easy to misdiagnose and miss diagnosis.Therefore,it is important for us to find out the independent risk factors of acute pulmonary thromboembolism clinically,which is very important for early diagnosis,prognosis and prevention of diseases.ObjectiveAt present,the relationship between blood lipid and the incidence and risk stratification of pulmonary embolism is not clear.In this study,the blood lipid level of 152 patients with suspected acute pulmonary thromboembolism was detected,and the difference between the APE group and the non APE group was compared with that of the non APE group,so as to explore the application value of the blood lipid in the acute pulmonary thromboembolism.Methods:A total of 152 suspected pulmonary thromboembolism patients admitted to Shangdong Province-owned Hospital from January 2016 to December 2017 were retrospectively reviewed.According to 2014ESC guidelines for acute pulmonary embolism,109 patients were included in the acute pulmonary thromboembolism(APE)group,and 43 in the non acute pulmonary thromboembolism(non APE)group.According to the sPESI score,the risk stratification of APE group was carried out.Blood lipids and lipoproteins were measured fasting during 24 hours after admission,while venous blood was taken to test D-dimers,troponin and brain natriuretic peptide.Data analysis is carried out by SPSS 24 software.Results:The results showed that the level of triglyceride(TG)in the APE group was significantly higher than that in the non APE group(1.60 ± 0.66 mmol/L vs.1.30±0.75 mmol/L,P<0.05),but the high density lipoprotein level(HDL)was significantly lower than that of the non APE group(1.07 ±0.27 mmol/L vs.1.25 ±0.36 mmol/L,P<0.01).Increased triglyceride levels increased the risk of acute pulmonary thromboembolism(OR=2.13,P<0.05),and high HDL levels,could reduce the risk of acute pulmonary thromboembolism(OR=0.156,P<0.01).The area under the ROC curve of triglycerides(AUC)was 0.674.Conclusion:Elevated triglyceride level is an independent risk factor for acute pulmonary thromboembolism,and high density lipoprotein is a protective factor.There was no clear relationship between blood lipid level and risk stratification of pulmonary embolism.For the patients with acute pulmonary thromboembolism,the detection of blood lipid is lack of specificity,but it is simple and easy to obtain.It is of certain significance for the early auxiliary identification and diagnosis of the disease,which can reduce the rate of missed diagnosis and improve the prognosis of the patients.