Clinical Study On The Treatment Of Knee Osteoarthritis Treated By Huayu Qushi Decoction Combined Exercise Therapy

Objective: To discuss and study the clinical efficacy of Huayu Qushi Decoction with exercise therapy for Early Knee Osteoarthritis(KOA).Method: According to the inclusion criteria to choose the first affiliated hospital of guangxi medical university bone had hospitalized patients with early diagnosis and treatment of 60 cases of knee osteoarthritis,according to random number table method divided the patients into the treatment group(Huayu Qushi joint exercise therapy group)30 cases and control group(Huayu Qushi),30 cases in treatment group,control group = 1:1.Treatment group give Huayu Qushi joint exercise therapy treatment,control group to exercise therapy treatment,treatment for 4 weeks,through the detection of serum inflammatory factors,KSS score evaluation function of knee joint,VAS score method compared two groups of clinical curative effect.Results:There was no comparability between the two groups before treatment(P > 0.05).Within two way contrast treatment,4 weeks after treatment compared with 2 weeks after treatment,the treatment of 8 weeks compared with 4 weeks after treatment,the knee score coefficient contrast are comparable(P < 0.05),the results suggest that the two groups after treatment of knee joint symptoms and functional activities have improved,with prolonged treatment,the better curative effect;At 4 weeks after treatment between the two way,two weeks after treatment,8 weeks after treatment were compared,the knee score coefficient contrast are comparable(P < 0.01),the results suggest that after treatment the knee KSS score in treatment group were higher than that of control group,treatment group,to improve the symptoms and function of knee joint is better than than the control group.There was no comparability of VAS scores in the two groups before treatment(P > 0.05).Within two way contrast treatment,4 weeks after treatment compared with 2 weeks after treatment,the treatment of 8 weeks compared with 4 weeks after treatment,the VAS score coefficient contrast are comparable(P < 0.05),the results suggest that the two groups after treatment of knee joint pain symptoms improved,with the extension of time,the curative effect is better;At 4 weeks after treatment between the two way,two weeks after treatment,8 weeks after treatment were compared,the knee score coefficient contrast are comparable(P < 0.01),the results suggest that the VAS score in treatment group were higher than the control group after treatment,the treatment group is better than the control group on the improvement of the knee joint pain symptoms.Two groups of patients before treatment TNF alpha in joint fluid,IL-6,IL-1 content compared with no significant difference(P > 0.05),the two groups in 8 weeks after treatment,the joint fluid of TNF alpha,IL-6,IL-1 in serum levels compared to before treatment were significantly lower(P < 0.05),said symptoms after treatment has obvious changes,the curative effect is obvious.After 8 weeks of treatment,there were significant differences in the levels of inflammatory factors in the two groups,indicating that the treatment group decreased the level of KOA inflammatory response compared to the control group.(P < 0.05)the total effective rate of the two groups after treatment was compared with that of Huayu Qushi Decoction unite exercise therapy.There were 9 cases of the improvement,12 cases with significant effect,8 cases improved,and 2 cases were invalid.Huayu Qushi group total effective a total of 10 cases,ineffective in all 3 cases,improved in 7 cases,of a total of 10 cases were markedly improved,by Huayu Qushi Decoction unite exercise therapy group total effectiveness 96.66%,Huayu Qushi Decoction group total effective rate was86.67%,P < 0.05,the difference between the two groups comparable,so in the early stage of the treatment group in improving KOA pain,improve the function of knee joint is better than the control group.Conclusion: Huayu Qushi Decoction party joint exercise therapy for knee osteoarthritis by early symptoms,can improve the knee joint activity,control the symptoms,inhibiting inflammatory reaction,improve the patients quality of life.