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Comparison Of Two Surgical Methods Of Neonatal Ileal End Perforation

Posted on:2019-09-28Degree:MasterType:Thesis
Country:ChinaCandidate:X X ChenFull Text:PDF
GTID:2394330545458149Subject:Surgery
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ObjectiveRetrospective analysis of 2014-June 2014-June Zheng Dasan establishing affiliated hospital pediatric general surgery treated 74 cases of neonatal necrotizing enterocolitis(NEC)caused by neonatal cases data terminal ileum perforation,and specific serum marker analysis with two kinds of operation method central Africa changes,hospitalization days and the case fatality rate,for the children to choose a more appropriate way of operation.Materials and MethodsAmong 74 NEC-induced neonatal ileal terminal perforation,12 of them were abandoned by their families due to heavy intraoperative abdominal infection and other reasons.The remaining 62 patients completed the surgery.According to the way of surgery,they were divided into the enterofistula group(n=33)and the enterotomy enterostomy group(n=29).Cases will be two sets of data for case-control,statistical data central African specific serological markers,including:c-reactive protein(CRP)and white blood cells(WBC),platelet(PLT),serum calcitonin(PCT),albumin,hospitalization days and case fatality rate data such as presence of differences between the two groups.The statistics software SPSS21.0 is used to process the data,where:for the counting data(%),we use the?~2 test.For the measurement data(x±s),t test of two independent samples was used.If the result does not conform to normal distribution,the rank sum test is used.ResultsA total of 62 of the 74 children underwent surgery and 12 gave up treatment.A total of 17 cases died(including abandoning treatment),with a mortality rate of 22.97%.After data analysis showed that 74 cases of terminal ileum perforation with serological markers of CRP,WBC,PLT,PCT,albumin are abnormal,the single factor analysis showed that CRP,PLT,PCT is associated with children with operation method.Compared with children in the group of enterotomy and enterostomy,CRP,PLT and PCT in the group of enterofistula surgery took a relatively short time to recover to the normal range,and the difference was statistically significant.And cut and colostomy group intestinal anastomosis group hospitalization days,mortality statistics analysis,found that children with intestinal colostomy surgery group average hospitalization days was:9.78+/-1.16,0 people died,mortality rate by 0%,and bowel intestinal anastomosis group average hospitalization days for children:12.23+/-1.78 killed 5people,mortality was 17.24%,intestinal colostomy surgery group has lower mortality and hospitalization days.ConclusionsFor children with NEC-induced ileal end perforation,the choice of intestinal fistula can shorten the time for serum markers to return to normal range,so that abdominal inflammation can be quickly controlled.Therefore,as one of the surgical methods of ileal end perforation,it is of great clinical significance.
Keywords/Search Tags:Gastrointestinal perforation, neonate, biomarkers, outcome
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