Therapeutic Effect Of Shuxuetongmai Granule On Qi Deficiency And Blood Stasis Syndrome In Acute Ischemic Stroke

Objective: Observed the clinical effect and safety of Shuxuetongmai granule in treating Acute ischemic stroke with deficiency of qi and blood stasis.Methods: According to the standard 180 cases of Acute ischemic strok-e with deficiency of qi and blood stasis patients by random number table is divided into treatment group(Shuxuetongmai granule treatment group),control group(conventional drug treatment group)and Chinese medicine control group(Naoxintong Capsule and conventional drug treatment group),each group has 60 patients.The control group to anticoagulation,lipid-lowering treatment,detecting vital signs,liver and kidney function,bloodcoagulation function;Treatment group on the basis of the control group with Shuxuetongmai granule;Chinese medicine control group on the basis of the control group with Nintong Capsule.Treatment for 2 weeks,efficacy was assessed using the Neurological Deficiency Score Scale(NIHSS),modified Barthel Index scale(m BI),TCM syndrome score,clinical efficacy,TCM syndrome efficacy,record adverse reaction and safety index data,the data differences between the three groups were compared and statistically analyzed,comprehensive Evaluation of Shuxuetongmai Granules in Treating Acute ischemic stroke with deficiency of qi and blood stasis Clinical Efficacy and Safety.Results: 1.The three groups were compared in terms of age,gender,basic illnesses,and bad habits,the difference was not statistically significant(P>0.05).2.Clinical efficacy:The total effective rate of reatment group was 93.1%,control group was 69.5%,Chinese medicine control group was 82.8%,the treatment group was better than the control group and Chinese medicine control group(P<0.05),Chinese medicine control group was better than the control group(P<0.05).3.TCM syndrome efficacy:The total effective rate of reatment group was 94.8%,control group was 72.9%,Chinese medicine control group was 82.8%,the treatment group was better than the control group and Chinese medicine control group(P<0.05),Chinese medicine control group was better than the control group(P<0.05).4.NIHSS score:the treatment group was better than the control group and Chinese medicine control group(P<0.05),Chinese medicine control group was better than the control group(P<0.05).5.m BI index:the treatment group was better than the control group and Chinese medicine control group(P<0.05),Chinese medicine control group was better than the control group(P<0.05).6.TCM syndrome score:the treatment group was better than the control group and Chinese medicine control group(P<0.05),Chinese medicine control group was better than the control group(P<0.05).7.Safety:Before and after treatment in all three groups,liver function,kidney function,blood coagulation function no significant change,the difference was not statistically significant(P>0.05).Conclusions: 1.Shuxuetongmai Granule can significantly improve the degree of neurological impairment in patients with acute ischemic stroke with deficiency of qi and blood stasiss,significantly improve their daily living skills.2.Shuxuetongmai granule combined with essential drugs for acute ischemic stroke with deficiency of qi and blood stasis syndrome is better than the treatment of basic drugs alone,and Naoxintong Capsule joint basic drugs.Moreover,no obvious side effects,have good safety.