| Objective:Objective to observe the irritable bowel syndrome(irritable b owel syndrome)of liver depression and qi stagnation Drome with const ipation,ibs-c)patients' psychological status and their gastrointestinal mu cosal blind passage time(orocecal transi time,OCTT).The effects of "qi regulating and heat regulating" on anxiety and depression and gastrointe stinal motility were observed.Methods:Of 250 patients with IBS-C Hamilton Depression rating Scale(Hamilton 'Scale,HAMD)and Hamilton anxiety Scale(Hamilton anxiet y Scale,HAMA)to measure,understand the psychological state of pati ents with IBS-C,and selected accord with mild and moderate anxietyD epression status of IBS-C(liver Depression and qi stagnation syndrome)patients 90 cases,randomly divided into 3 groups,western medicine gr oup with lactulose oral liquid fluorine pp thiamethoxam tons of beauty QuXin treatment,Chinese medicine group with adjustable gas heat treat ment,The combination group was treated with western medicinegroup a nd Chinese medicine group.All three groups were treated for 3months.Clinical observation and statistical analysis of OCTT,HAMD and HAM A before and after treatment were conducted in all groups.Results:(1)Mental status of 250 IBS-C patients:114 men and 136 wo men,and 116 patients with mild or moderate anxiety and depression,w ith an incidence rate of 46.4%;There are 53 anxiety patients in total,a nd the incidence rate is 20.8%;There are 37 patients with depression and the incidence rate is 14.8%;There were 27 patients with anxiety and depression,and the incidence rate was 10.08%;Among them,ther e was no significant difference between women and men in anxiety,de pression,or anxiety combined with depression(P>0.05).(2)Clinical effica cy:After treatment,the total effective rate of the Chinese medicine gro up was 80%,the total effective rate of the Western medicine group w as 66.67%,and the total effective rate of the combined group was 93.1%.The difference between the combined group,the Chinese medicine group and the Western medicine group was statistically significant(P<O.05).The combined group was better than traditional Chinese medicine g roup and Western medicine group(P<0.05),and traditional Chinese medi cine group was better than Western medicine group(P<0.05).(3)Clinical symptom score:?total score:Joint group and Chinese medicine group,Western medicine group total clinical symptom score difference has stati stical significance(P<0.05),joint group is better than Chinese medicine group,Western medicine group;The traditional Chinese medicine group is superior to the Western medicine group.There was a difference bet ween the three groups of total clinical symptoms before and after the tr eatment(P<0.05),which was better than before the treatment(P<0.05).?Comparison between clinical symptom accumulation groups:There was no significant difference in the total clinical symptom scores(P>0.05)be fore treatment in each group.After the treatment,the total clinical sym ptom scores of the combined group,the traditional Chinese medicine gr oup,and the Western medicine group were statistically significant(P<0.05).The combined group was superior to the traditional Chinese medicin e group and the Western medicine group,and the traditional Chinese m edicine group was superior to the Western medicine group.In the grou p,there was a difference before and after the total clinical symptom sc ore treatment(P<0.05),which was better than before the treatment.(P>0.05).?There was no statistically significant difference in the points of c linical symptoms in the first three groups of patients(P>0.05).After the treatment,the two groups were compared:the combined group and the Chinese medicine group:the abdominal pain frequency the degree of a bdominal pain the degree of abdominal distension,the satisfaction of de fecation,and the effect on life and the Chinese medicine group were st atistically significant(P<0.05).The combined group is superior to the tra ditional Chinese medicine group.Combined group and Western medicine group:Combined group abdominal pain frequency,abdominal pain deg ree,abdominal distension degree,bowel satisfaction,impact on life,belc hing hiccup,chest tightness and discomfort compared with Western med icine group was statistically significant(P<0.05).The combined group w as superior to Western medicine group.Chinese medicine group and We stern medicine group:Chinese medicine group abdominal pain frequency and degree,abdominal distension degree,bowel satisfaction,impact on life,belching Qi hiccup,chest tightness and discomfort compared with Western medicine group has statistical significance(P<0.05),Chinese m edicine group is better than Western medicine group.?Compared with the group,the three groups were compared before and after treatment:Joint group:There was a difference in clinical symptom scores before a nd after treatment(P<0.05),and it was better than before treatment after treatment;Chinese medicine group:abdominal pain frequency,abdomin al pain degree,abdominal distension degree,bowel satisfaction,impact on life,chest tightness and discomfort,belching hiccup before and after treatment(P<0.05),better than before treatment;Western medicine grou p:abdominal pain frequency,abdominal pain,abdominal distension befo re and after the treatment has statistical significance(P<0.05),after the t reatment is better than before the treatment;However,there was no stat istical significance before and after the treatment of bowel satisfaction,life effects,chest discomfort,belching hiccups,and chest inflamed pain(P>0.05).(4)Analysis of the results before and after the treatment of H AMD,HAMA,and OCTT in three groups:The comparison between gr oups:HAMD,HAMA,and OCTT in the first three groups of patients were not statistically significant(P>0.05).After the treatment,the HAM D,HAMA,and OCTT of the combined group,the Chinese medicine gr oup,and the Western medicine group were statistically significant(P<0.05).The difference between HAMD,HAMA and Western group was stat istically significant(P<0.05).The difference between HAMD and HAMA was statistically significant compared with that of Western medicine gr oup(P<0.05).The effective rate after HAMD treatment:the total effectiv e rate of the combined group was 89.66%,the total effective rate of t he Chinese medicine group was 83.3%,the total effective rate of the Western medicine group was 76.67%,and the effective rate after HA MA treatment was:the effective rate of the combined group was 93.10%,the Chinese medicine group was 70%,and the Western medicineg roup was 66.67%.%,The efficiency of combined group is better than that of traditional Chinese medicine group and Western medicine group.Combination group and Chinese medicine group OCTT had different st atistical significance compared with Western medicine group(P<0.05).?In the group,the differences between HAMD,HAMA and OCT were s tatistically significant(P<0.05),compared before and after treatment betw een the three groups of patients,and were superior to those before trea tment.Conclusions:(1)The Qi and heat treatment method has the effect of r elieving liver depression and facilitating defecation,and can improve th e clinical symptoms of patients with mild or moderate anxiety and depr ession in IBS-C,unilateral or combined lactofructose and fluperothione tons of Mertrixine tablets;It can obviously improve the clinical sympto ms of abdominal distension,abdominal pain,and constipation in patient s,and achieve satisfactory results.It is worth promoting.Its mechanism of action may play a role in the regulation of microecology and brain-intestinal axis,and further research is needed.(2)IBS-C has a state of anxiety and depression.The OCTT time is extended.The state of anxi ety and depression is improved after intervention by the Qi and heat tr eatment,and the OCCT time is shortened. |
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