Clinical Observation On Treatment Of Lumbar Disc Herniation Of Qi Stagnation And Blood Stasis Syndromes By Gen Tong Yin Cream Combined With Ironing Therapy

Objective: To observation the clinical efficacy and the incidence of gastrointestinal adverse reactions of treating lumbar disc Herniation with qi stagnation and blood stasis syndrome by observing gen tong yin cream combined with Chinese medicine ironing therapy.By comparing the ifferences in clinical efficacy and the impact on inflammatory factors of diclofenac sodium sustained-release tablets combined with traditional Chinese medicine ironing therapy for lumbar disc herniation qi stagnation and blood stasis syndrome,thus,exploring the mechanisms that improve the symptoms and signs of patients,Provide a theoretical basis for promoting clinical use.Methods: Selected patients who were treated at the out-patient department of Spine Surgery and Inpatient department of Ruikang Hospital affiliated to Guangxi University of Chinese Medicine from February 2016 to December 2017,60 patients who met the inclusion criteria for lumbar disc herniation were randomly assigned to the observation group and the control group,30 cases in each group.Based on common conventional therapies,the observation group given gen tong yin cream with Chinese medicine ironing therapy,and control group received oral diclofenac sodium sustained release tablets with ironing therapy.2 weeks for a course of treatment,lumbar disc herniation treatment for 4 weeks.Testing indexes of all cases who at the time before treatment,treatment about 2 weeks and 4weeks.To test the patient's lower lumbago pain rating scale(JOA),Visual analog scores(VAS)for pain index,Interleukin-6(IL-6),clinical effective rate and Incidence of adverse reactions in the digestive tract.The resulting data was statistically analyzed using the SPSS 17.0 statistical software package.Results:1.There was no statistically significant difference in age,gender,duration of disease,and site of disease between the two groups(P>0.05),and they were comparable.2.After 4 weeks of treatment in both groups,the total effective rate in the observation group was 73.3%,and the total effective rate in the control group was 83.3%.There was no significant difference between the two groups in clinical efficacy(P=0.115>0.05),so for the patients with improved symptoms of lumbar and leg pain,lumbar function,daily work and life,the two groups have similar efficacy with no significant statistical difference.3.Compared with the JOA scores of patients,there was no significant difference between the observation group and the control group before treatment,P>0.05.The difference between the two groups of patients after treatment for 2 weeks or 4 weeks and before treatment was statistically significant(P<0.05).There was no significant difference in JOA scores between the two groups(P>0.05).It shows that the symptoms are relieved and the functions are gradually restored.All have certain curative effect.The observation group's treatment effect is similar to that of the control group.4.The VAS score before treatment was P>0.05.There was no statistical difference between the two groups,and they were comparable.Comparison of VAS scores between 2 weeks of treatment and 4 weeks of treatment compared with before treatment and within groups,that the difference was statistically significant(P<0.05).The VAS score after 2 weeks of treatment and treatment for 4 weeks was not was not statistically significant(P<0.05).There was no significant difference between the two weeks of treatment and the four weeks of treatment in the control group(P>0.05).It was indicated that both the observation group and the control group were able to relieve pain,and the effects were similar,with no significant difference.5.On two weeks of treatment compared with before treatment,there was no significant decrease in interleukin-6 between the observation group and the control group(P>0.05).After 4 weeks of treatment,the level of interleukin-6 decreased,(P<0.05).Interleukin-6 levels decreased after 4 weeks of treatment(P<0.05).There was no significant difference between the two groups in the observation point of interleukin-6(P>0.05).Both the observation group and the control group could reduce the interleukin-6 level,and there was no significant difference.6.There was no adverse reaction in the observation group,but three adverse reactions occurred in the control group.Safety test P<0.05,So the safety of the observation group was better than that of the control group.Conclusion: The treatment of LDH qi stagnation and blood stasis by the combination of gen tong yin cream and ironing therapy can effectively reduce the level of elevated interleukin-6,improve the lumbar symptoms of the patient,and restore the function of the lumbar and leg,and the therapeutic effect was similar to that of the non-steroidal anti-inflammatory drug diclofenac sodium sustained-release tablets,with no significant difference.Treating lumbar intervertebral disc herniation with the combination of gen tong yin cream combined with ironing therapy and the use of non-steroidal anti-inflammatory drug diclofenac sodium sustained-release tablets combined with ironing therapy have the similar effect,and the incidence of gastrointestinal adverse reactions of gen tong yin cream is less.