DWI MRA And Clinical Correlation Analysis Of Acute Cerebral Infarction

Objective:The clinical risk factors of acute cerebral infarction were whether or not there were vascular stenosis and vascular stenosis.And the relationship between rADCA and NIHSS score in acute cerebral infarction.Methods:A total of 130 patients with acute cerebral infarction hospitalized from March 2016 to November 2017 in Department of Neurology,the first affiliated Hospital of Southern Anhui Medical College,were collected.All the selected patients were in accordance with the guidelines for the diagnosis and treatment of acute ischemic stroke established by the Neurology Branch of the Chinese Medical Association in 2014.There were 83 cases of single focus and 47 cases of multiple foci.All the patients were classified as acute cerebral infarction by the DWI and ADC values of the skull.The clinical manifestations of the patient were consistent with the focus demonstrated by the imaging.Collect general data of all patients?sex,age,history of hypertension,history of hyperlipidemia,history of smoking and drinking,history of diabetes,history of coronary heart disease,history of atrial fibrillation?.Whether or not there is a history of cerebral infarction,symptoms and signs of the patients at admission,head CT and MRI?T1.T2.T2-FLAIR.DWI.MRA?,and other related examinations,such as cervical vascular ultrasound,and so on.The rADC values of 83 patients with single focus were calculated.Before the MRI examination,two chief neurologists scored each patient with NIHSS and took the average of them as the final NIHSS score.The correlation between rADC and clinical NIHSS score was analyzed by Spearman correlation.Two independent samples were tested by t-test.The risk factors were compared with the four grid card square test.To summarize the risk factors of patients with acute cerebral infarction,The presence and distribution of stenosis in MRA were related to the clinical risk factors.and the relationship between rADC,MRA and clinical NIHSS score,so as to prevent the patients with cerebral infarction.Diagnosis and prognosis provide reference basis.Results:1.The male to female ratio of acute cerebral infarction was 1.5:1,the onset age was31-90 years old,the average age was 66.48±10.72 years old,the average ADC value of all patients was 12.97±3.19 days,the ADC value was?3.58-6.57?×10^-4mm2/s,and the average was?4.58±1.22?×10^-4mm2/s,rADC=0.55±0.20.2.The risk factors for acute cerebral infarction were hypertension in 95 cases?73%?,diabetes in 35 cases?27%?,smoking history in 30 cases?23%?,hyperlipidemia in 26cases?20%?,drinking history 20 cases?15%?,history of cerebral infarction 13 cases?13?,atrial fibrillation in 15%cases,and coronary heart disease cases in cases.3.Vascular stenosis in patients with acute cerebral infarction 50-69 years 42 cases and70-90 age group in 34 cases,smoking,50-69 year old group and 70-90 years age group,diabetes mellitus,history of atrial fibrillation were significantly different?P<0.05?,of which 50-69 years old group,smoking,drinking,diabetes was significantly higher than the proportion of 70-90 year old age group,but the ratio was significantly lower than that of 70-90 cases of atrial fibrillation the age group.4.The rADC value?0.55±0.20?of 83 patients with single acute cerebral infarction was negatively correlated with NIHSS score?P<0.05?.5.There were significant differences in hypertension,hyperlipidemia,smoking,alcohol consumption,diabetes mellitus and cervical vascular plaque between the stenosis group and the non-stenosis group?78 cases in the acute cerebral infarction group and 52 cases in the non-stenosis group,P<0.05?.The proportion of hypertension,hyperlipidemia,smoking,drinking,diabetes and cervical vascular plaque in the stenosis group was significantly higher than that in the non-stenosis group.6.There were 31 cases of simple anterior circulation stenosis group,15 cases of simple posterior circulation stenosis group and 84 cases of mixed stenosis group in patients with acute cerebral infarction.There was a significant difference in the history of cerebral infarction between simple anterior circulation stenosis group?1 case?and simple posterior circulation stenosis group?5 cases??P<0.05?.The proportion of history of cerebral infarction in simple posterior circulation stenosis group was significantly higher than that in simple anterior circulation stenosis group.7.There were 46 patients with single stenosis and 32 patients with multiple stenosis in acute cerebral infarction group.There was only significant difference in diabetes history between single stenosis group and multiple stenosis group?P<0.05?.The proportion of diabetes mellitus in single stenosis group was significantly lower than that in multiple stenosis group.8.There was significant difference in clinical NIHSS score between the two groups?P<0.05?.The clinical NIHSS score in the stenosis group was significantly higher than that in the non-stenosis group?P<0.05?.Conclusion:1.The higher the rADC value of patients with acute cerebral infarction,the lower the clinical NIHSS score.2.Smoking,drinking and diabetes were the main risk factors for people aged 50 to 69,and atrial fibrillation was the main risk factor for people aged 70 to 90.3.Patients with high blood pressure,hyperlipidemia,smoking,alcohol consumption,diabetes,and cervical vascular plaque are at risk of intracranial vascular stenosis.Patients with a history of cerebral infarction are prone to simple posterior circulation stenosis.Patients with a history of diabetes are prone to multiple vascular stenosis.4.Patients with acute cerebral infarction with stenosis had high clinical NIHSS score and poor prognosis.