| Research purposes:In this study,self-control study method was used to treat 59 patients with chronic asthmatic asthma as the object of study.Observe changes in eosinophils,allergen total IgE,cholesterol,triglycerides,and other biological indicators before and after treatment.At the same time,analyze and summarize the basic information of patients and summarize the clinical features of patients with bronchial asthma,observe the improvement of clinical symptoms,and explore the effects of Wenrun Xinjin Peiben’s prescription on the above-mentioned relevant clinical indicators,enrich the clinical treatment of the chronic duration.of bronchial asthma and provide a reference for the clinical treatment of chronic asthmatic asthma.Methods:A total of 59 chronic asthmatic patients with chronic bronchial asthma who met the inclusion criteria were collected from October 2015 to March 2018.The patients aged between 18 and 75 years old agreed to participate in the study and signed the informed consent form.Fill out the study observation form.Using the self-control study method,the patients were given oral.administration of Wenrun Xinjin Peiben’s prescription.The specific prescriptions were:Astragalus membranaceus 45g,Radix Aconiti(first fried)15g,Guizhi 30g,dried ginger 18g,cinnamon 15g,Magnolia officinalis 15g,white Pelican 15g,ebony 18g,schisandra 30g,medlar 15g,raw licorice 12g,a total of 11 species,and according to the clinical symptoms of addition and subtraction.Water decoction,1 dose per day,divided into 2 times,take medicine after morning and evening meals,1 month after treatment,information collection and clinically relevant biological indicators were performed again.Eosinophils,allergens total IgE,cholesterol,triglycerides,TCM syndrome scores were compared before and after treatmentand.An Excel database was established and SPSS20.0 statistical software was used for data processing.Measured data were expressed as mean ± standard deviation(x±S),and count data was expressed as a composition ratio.The paired t test was used for the normal distribution before and after the data comparison.Those who do not meet the normal distribution use the signed rank and inspection.The difference was statistically significant when P<0.05.Results:1.The use of Wenrun Xinjin Peiben’s prescription for the treatment of 59 cases of chronic asthma patients with chronic continuation before and after their own control,after treatment eosinophils decreased compared with before treatment,the difference was statistically significant(p<0.05).2.The total IgE of allergens after treatment was lower than before treatment,and the difference was statistically significant(p<0.05).3.After treatment,cholesterol decreased compared with before treatment,and the difference was statistically significant(p<0.05).4.There was no significant difference in triglyceride after treatment(p>(0.05).5.The application of Wenrun Xinjin Peiben’s prescription in the treatment of 59 cases of patients with chronic asthmatic bronchitis through their own before and after the control,the results showed that the clinical cure rate was 0,significant efficiency 37.3%(22 cases),effective rate 62.7%(37 cases),inefficiency 0.6.The TCM syndrome scores of patients after treatment were lower than those before treatment.The difference was statistically significant(p<0.05).Conclusion:1.Indicating that Wenrun Xinjin Peiben’s prescription has good effects on airway inflammation,airway hyperresponsiveness,allergic state and prognosis of patients with chronic asthmatic asthma by adjusting lung and spleen function.2.Wenrun Xinjin Peiben’s prescription has obvious improvement effect on the symptoms of bronchial asthma patients,and has good safety in treatment,which is in line with the core pathogenesis of lung and spleen deficiency in the chronic duration of bronchial asthma. |
PDF Full Text Request