| Objective:Through the collection of clinical cases of thyroid nodules,statistical methods are used to analyze the modern etiology and pathogenesis of thyroid nodules,to explore the distribution of TCM syndrome types of thyroid nodules,to enrich the content of TCM syndrome differentiation,and to better guide the treatment of clinical medicine.Methods:In this study,125 patients with thyroid nodules were studied in Dongzhimen hospital.The general data(sex,age occupation,etiology,smoking history,drinking history,family history,family history,)symptoms and signs and laboratory indexes of thyroid function were collected.T test,chi square test,Wilcoxon rank and test,Spearman method was used to analyze the correlation among thyroid nodules,general data,symptoms,syndromes and laboratory indexes.Results:1.A total of 125 patients were included in the study,15 of which were male,accounting for 12%of the total cases,110 of the female patients,accounting for 88%of the total number of studies.The prevalence of female thyroid nodules is significantly higher than that of men,with a ratio of 7.3:1.In this study,the age distribution is in the range of 10-89,the youngest patient is 13 years old,the oldest is 86 years old.The average age of onset was 47.9 + 14 years.The 40-49 year old age group accounted for the largest proportion,followed by 50-59 years and 30-39 years old two age groups.From the occupational distribution,among the 125 cases,the white-collar workers were the most,with a total of 56,accounting for 44.8.%of the total number,followed by retirees,31 people,and the proportion of illness accounted for 24.8%.The main causes of thyroid nodules are overwork and emotional internal injury.2.the main symptoms of this study,the symptoms of more than 30%,were deity,insomnia,sore throat or thirst,cough and phlegm,chills,irritability,irritability,swelling of the face,swelling of the neck,palpitation,unformatting of the stool,hot hand,heart or five heart trouble,neck suffocation or obstruction of the neck,heavy body,dysphagia,or no Chinese Chest tightness,digestive tract infection,constipation of the 16;the mental fatigue,insomnia,thirst,throat or above 60%.Neck symptoms,neck swelling in 43 people,accounted for 34.4%;neck suffocation or obstruction of 40 people,accounting for 32%;cervical enlargement of 35 patients,accounting for 28%;sore and throat patients 18,accounting for 14.4%.The highest frequency of tongue,pale dark tongue,dark red tongue and the tongue,thin white fur.The pulse in the sink veins and veinlets appear most frequently,followed by pulse string pulse.3.The frequency of common syndromes of thyroid nodules from high to low is the following:spleen and kidney yang deficiency,yin deficiency and fire prosperity,Qi and yin deficiency,phlegm and blood stasis,liver depression and spleen deficiency,qi stagnation and phlegm resistance,liver fire flourishing.Of the 7 patients with strong liver fire syndrome,100%were irritable and irritable,85.71%had symptoms of dry sore throat or thirst,71.43%had symptoms of constipation,71.43%had symptoms of pain,71.43%of the patients were afraid of heat,followed by symptoms such as stool and yellow,swollen and sore throat,low back and knee,cough and phlegm.Shape.Of the 8 patients with qi stagnation and stagnation of phlegm,87.5%had dizziness and dizziness,75%had neck suffocation or obstructive symptoms,and 62.5%had coughing and phlegm.Of the 15 patients with Phlegm Blood Stasis Syndrome,80%of the patients had dizziness and dizziness,73.33%had facial pigmentation symptoms,73.33%had menstrual black with clot and amenorrhea,66.67%of the patients had insomnia,followed by symptoms such as fatigue and fear of cold.Among the 11 patients with liver depression and spleen deficiency syndrome,81.81%of them had the symptoms of chest distress and epigastric epigastric,72.72%were dizzy and dizzy.72.72%of the patients had the appearance of pale yellow or no Chinese,72.72%of the patients had unformed stool,and the second was the symptoms of neck suffocation or obstruction and fatigue.Of the 27 patients with Yin deficiency syndrome,85.19%of the patients had the symptoms of dry throat or thirst.81.48%of the patients had symptoms of hand,foot and heart fever or five heart trouble,81.48%of the patients had insomnia,followed by fatigue and irritability.Of the 26 patients with Qi Yin two deficiency syndrome,84.62%of the patients had the manifestation of fatigue strength,61.54%of the patients had the symptoms of dry sore throat or thirst,61.54%of the patients had the fear of cold,61.54%of the patients had the symptoms of dizziness,dizziness,insomnia and other symptoms.Of the 31 patients with spleen and kidney yang deficiency syndrome,83.87%of the patients had the symptoms of heavy body weight,80.65%of the patients had facial swelling symptoms,74.19%of the patients had the fear of cold,74.19%of the patients had the performance of fatigue,followed by dry throat or thirst,insomnia and other symptoms.4.From the age distribution,125 patients with qi stagnation,phlegm stagnation,liver fire,phlegm and blood stasis,liver depression and spleen deficiency,yin deficiency and fire flourish are many,and the old people of deficiency of Qi and Yin and yang deficiency of spleen and kidney are more.From the occupational distribution,among the 125 patients,the peasants were dominated by Yin deficiency and fire prosperity.The cadres were mainly with liver fire and yin deficiency and fire prosperity.The white collar was dominated by deficiency of Qi and Yin and yang deficiency of spleen and kidney.The main body was Yang deficiency of spleen and kidney and yin deficiency and fire flourish.The teachers were mainly with liver fire,and the retirees were mainly spleen kidney yang deficiency and Qi Yin deficiency.From the course of the disease,the first stage was qi stagnation phlegm resistance,liver fire exuberant,Phlegm Blood Stasis Syndrome the most,middle stage with Yin deficiency fire flourish,liver depression and spleen deficiency syndrome mainly,later period mostly Qi Yin deficiency,spleen kidney yang deficiency syndrome mainly,recurrence period with Yin deficiency fire flourish,spleen kidney yang deficiency syndrome is more common.5.0f the 125 patients,71 of the patients with thyroid nodules involved,56.8%of the patients,65 of the patients involved in the spleen,52%,44,35.2%,23,18.4%,15,15,and 12%.The course of the disease involved in the liver is more in the early stage and in the recurrence period;the disease involved in the lung is more in the prophase;the disease involved in the heart is more in the middle period;the disease involved in the spleen and kidney is more in the later period and in the recurrence period.6.Of the 125 patients,53 were Yin deficiency and 42.4%;37 were Qi deficiency and 29.6%;31 were Yang deficiency and 24.8%;23 patients belonged to phlegm coagulation and 18.4%;19 patients were qi stagnation and 15.2%;15 patients belonged to blood stasis,accounting for 12%;7 patients belonged to fire fever;Among them,deficiency syndrome includes Yin deficiency,Yang deficiency and Qi deficiency,a total of 121 cases,including 64 cases of phlegm coagulation,qi stagnation,blood stasis and fiery fever.The course of the patients in Yin deficiency is in the medium and recurrent periods,and the course of the Qi deficiency is more in the middle and later stages.The course of the patients in Yang deficiency is more in the later period and in the recurrence period.The patient's course of phlegm coagulation,qi stagnation,blood stasis and hot fever is more in the early stage.The main period is deficiency syndrome.7.in this study,86 thyroid function indexes were statistically analyzed,and TT4 showed a significant difference in the distribution of syndromes.Among the 86 patients,the TT4 index was the highest in the patients with Yin deficiency and fire hyperactivity syndrome,which was 9.87 + 1.67,and the lowest in the spleen kidney yang deficiency syndrome was 6.76 + 1.18.Index TT3 abnormal patients in the middle period,one in the late stage;index TT4 were normal;index FT3 abnormal 1 in the middle period,2 in the later period,1 in the recurrence period;index FT4 abnormal 1 in the early stage,2 in the late stage,1 in the recurrence period;index of abnormal patients 1 in the early stage,1 in the middle of the period.During the period,4 were in the late stage and 1 were in the recurrence period.Conclusion:1.thyroid nodules occur mostly in women.The average age of male onset is higher than that of women.2.the most frequent symptoms of thyroid nodules were fatigue,insomnia,dry throat or thirst.The frequency of common syndromes from high to low is the following:spleen and kidney yang deficiency,yin deficiency and fire prosperity,Qi and yin deficiency,phlegm and blood stasis,liver depression and spleen deficiency,qi stagnation and phlegm resistance,liver fire flourishing.And age,occupation,course of disease are related to syndrome type.3.in the early stage,it was mainly empirical evidence,and the deficiency syndrome was the main medium-term,late stage and relapse stage.4.Early thyroid nodules mainly involve liver and lung.The middle stage mainly involves the heart and spleen.Later stage mainly involves the kidney,and the recurrence mainly involves the liver,spleen and kidney.5.early stages of disease are mainly phlegm coagulation,qi stagnation,blood stasis and fire fever.The middle period is mainly Yin deficiency and Qi deficiency,and the main stage is Qi deficiency and yang deficiency,and the main recurrence period is Yin deficiency and yang deficiency.6.When thyroid nodules develop to the middle and late stages,thyroid function changes are easy to occur. |
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