| BackgroundAnal fissure as anal disease one of the most common diseases,the incidence tends to be younger in recent years.Rapid rhythm of life,poor eating habits,mental stress are too large lead to the incidence of anal fissure significantly increased,most patients use hemorrhoids suppository,relieve symptoms of acute phase,then repeated attacks,pain again-bleeding-constipation,vicious circle,Seriously affect the quality of life.At present,non-surgical treatment of Western medicine and more symptomatic treatment-based,surgical treatment with a variety of surgical procedures,resulting in a higher risk of incontinence.Chinese medicine treatment of the disease has obvious advantages,Chinese medicine oral treatment,the level of treatment of different doctors,the effect has its advantages and disadvantages,and long-term oral administration of Chinese herbal medicine patients difficult to adhere to.External treatment of traditional Chinese medicine treatment of anorectal disease has a unique advantage,convenient access to the affected parts,cheap,direct access to the disease,the effect is better,the patient is easy to accept,no obvious side effects.But the fact that patients are prone to recurrent episodes has become the key to the treatment of anal fissure.Western medicine for the cause of anal fissure,the latest research shows that the resting anal anal sphincter pressure and postconditioning ischemia is fundamental,and Chinese medicine treatment of spasm and pain on the basic research is mature,lack of clinical trials,so carry out this test.ObjectiveTo discuss the theoretical basis of anal fissure from the theory of liver treatment,combined with the latest etiological research results of anal fissure,dialectical treatment of Shuganjiyue,promoting blood circulation analgesia for the law,the antispasmodic analgesics combined with activating blood stasis medicine to help myogenic hemostatic drugs External use,explore the establishment of anal fissure new Chinese medicine treatment.In order to reduce the anal canal pressure in the quiescent phase of the patient and promote the blood circulation in the midline ischemic area after the anal canal,the patient's pain,hemorrhage and edema are alleviated,the healing of the ulcer surface is accelerated,and the recurrence of anal fissure is reduced.MethodsAccording to the randomized controlled experimental design,patients diagnosed with chronic anal fissure in clinic,university and society were selected and randomly divided into groups.The suppository was given by antispasmodic and analgesic drugs combined with blood circulation and stasis medicine group 2/day(morning and evening)Anal treatment;control group given Ma Yinglong hemorrhoids suppository anal 2/day(morning and evening 1)treatment.After 14 days of treatment,the two groups were scored according to the symptom of treatment,the standard of efficacy evaluation and the statistics of the scores of hemorrhage,pain,edema and wound healing of anus ulcer before treatment,on the 7th and 14th days of treatment,followed up The number of re-treatment after 3 months,the data analysis.Result1.The two groups of patients in the treatment of d7,d14 statistical hemorrhage,the pain does not have statistical differences,the experimental group to alleviate the symptoms of the basic consistent with the control group;2.The edema score of the two groups were significantly different from the control group in the treatment of d7,d14,P = 0.005,P =0.000,P<0.05,and the edema reduction effect of the experimental group was significantly better than that of the control group;P =0.004,P<0.05 with statistical significance,with the passage of treatment time,the experimental group wound healing effect is better than the control group;3 months after treatment,the test group recurrence frequency was significantly lower than the control group P=0.000,P<0.05 with statistical difference;3.The total curative effect of two groups was compared,the test group of 31,cured 17,the cure rate was 54.84%,the control group of 31 people,9 were cured,the cure rate was 29.03%;P = 0.048,P<0.05 overall efficacy test group was significantly better than Control group.Conclusions1.Under the theoretical guidance of differentiation of symptoms and signs of traditional Chinese medicine,disease differentiation and dialectical combination,the experiment basically established the etiology and pathogenesis of anal fissure from the liver on the rule;established the TCM "Shu gan jie yue huoxuezhitong" rule of law,prescriptions to Shaoyao Gancao Decoction mainly drugs plus blood circulation and blood stasis,supplemented by Baiji live muscle and blood,made suppository anal anal external treatment of chronic anal fissure.2 antispasmodic analgesics combined with blood circulation drugs can relieve topical analgesia in patients with chronic anal bleeding,pain,symptoms,and Ma Ying-long hemorrhoids suppository flush.However,in relieving edema,promote wound healing,reduce recurrence is better than Ma Yinglong hemorrhoids suppository.3.Antispasmodic analgesic drugs combined with the efficacy of suppository of blood circulation and stasis drugs may be related to the antispasmodic mechanism of peony licorice,frankincense,myrrh and the mechanism of promoting blood circulation,the mechanism of promoting recovery of Bletilla striata,and comprehensively improve resting anal sphincter pressure,Improve the anal canal after ischemia. |
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