The Establishment Of The Basis For Identification Of Dyslipidemia And Phlegm And Blood Stasis Syndrome Based On Expert Questionnaire And Its Clinical Verification

In view of the syndrome of dyslipidemia and phlegm stasis syndrome in the literature research and clinical practice,its identification standard is only divided into 5 kinds of syndromes,such as phlegm obstruction syndrome,spleen kidney yang deficiency syndrome,liver kidney yin deficiency syndrome,yin deficiency yang hyperactivity syndrome and qi stagnation and blood stasis syndrome,without phlegm and blood stasis in various frequently cited documents,such as "the guiding principle of clinical research on new drugs of traditional Chinese medicine" 1 In conclusion,the identification standard of this syndrome is mostly self prepared or synthesized,and lacks the identification standard of this certificate standard.Through literature analysis,expert questionnaire analysis,clinical verification and other methods,the identification basis of blood lipid abnormal phlegm and stasis syndrome is studied.The importance of the symptoms and the judgment basis of the primary and secondary symptoms are obtained by the cumulative percentage of statistics,the degree of coordination and the mean number analysis.The establishment of syndrome diagnosis difficulty provides the research mode,and lays the foundation for the identification and treatment of dyslipidemia syndrome.OBJECTIVE:To establish the identification basis of the syndrome of dyslipidemia,phlegm and blood stasis.METHOD1.LITERATURE RESEARCHIn the past 20 years,the literature of syndrome differentiation of dyslipidemia,phlegm and stasis is clearly defined,and the symptom description words are widely collected and established by establishing database to manage the syndrome of phlegm and blood stasis.2.EXPERT QUESTIONNAIREAccording to the results of literature analysis,expert questionnaire was developed.The first and second rounds of evaluation indicators were mainly about the importance,cumulative percentage and degree of coordination of symptoms.The cumulative percentage reflects the recognition degree of the experts to the symptoms,that is,the cumulative importance of symptoms.The higher the cumulative percentage,the more important the symptom is.The degree of degree of coordination,the degree of divergence of experts' opinions on the importance of symptoms,the smaller the degree of divergence,the more important the symptom is.According to the cumulative percentage>70%,the symptoms were screened by the coordination degree<0.40,and the cumulative percentage and the degree of coordination were calculated on the basis of the importance of the symptoms.Two rounds of questionnaires set up open questions,supplemented symptoms,and consulted experts on related issues.The third round of questionnaire method distinguished the first two rounds of questionnaires,using the degree of importance coordination and the average number analysis to select the importance of the symptoms and the definition of the primary and secondary symptoms.According to the definition and the characteristics of the index,the more important it is,the more the degree of coordination is less,the more strong the concentration of the experts.Therefore,the larger the mean,the better the degree of coordination is.The definition of the average number:This study uses the 5-Likert scal five point scale to classify the symptoms and make 5 scores on the importance of the symptoms according to the principle of equal difference.According to the principle of equality,the "very important,important,general,unimportant,very unimportant" grade is given to "5,4,3,2,1" respectively,and the "very important" is selected."Important"(5,4)the score of main symptom is more than 4 sets.Select the "general"score set for the second disease,that is greater than or equal to 3 and<4.The definition of coordination degree:according to the results,the variation coefficient 0.14?0.31,and according to the data distribution,select the degree of coordination<0.20 to determine the main disease;coordination degree<0.30,and the degree of coordination degree>0.20 to be secondary.Therefore,according to the mean value of more than 4,the degree of coordination<0.20 determines the main symptoms.The average number is more than 3,and the average number is<4,the degree of coordination is<0.30,and the degree of coordination is>0.20.3.RESULTS OF CLINICAL STUDYAccording to the results of the expert questionnaire,the clinical questionnaire was used to carry out the clinical survey of small samples.The patients who were clearly diagnosed as abnormal blood lipid were recorded by checking the outpatient electronic medical records and hospitalized medical records,and the patients came to participate in the study by telephone communication.In the syndrome of dyslipidemia phlegm and blood stasis syndrome patients,and the diagnostic information in the questionnaire check.The definition of primary and secondary disease was verified.CONCLUSIONAccording to the literature,the expert questionnaire and the clinical study,the identification basis of the syndrome of dyslipidemia and phlegm stasis is the main symptom:obesity,body weight,mouth sticky,chest tightness,heavy limbs,purple tongue,tongue ecchymosis,thick moss and greasy fur.Secondary symptoms:fatigue,vertigo,skin nail,eye canthus,palate,palate,dyspaicus,prickle in the front of the heart,abdominal distention,vomiting and sputum saliva,nausea or vomiting,tongue veins,slippery moss,astringent veins and slippery veins.