| Objective:According to the experience in the Hiding Perverse Trend Rationale curing disease of the past medical expert.To explore the Hiding Perverse Trend Rationale conducts the treatment and invasion of IgAN.After the observation and evaluation of clinical effectiveness,to establish the system of the Hiding Perverse Trend Rationale and diagnosis formula applies in healing the IgAN.Drawing a conclusion of Doctor Lixia who makes the medical diagnosis formula in application of the Hiding Perverse Trend Rationale.Material and Technique:The cases are all from the outpatients of identified IgAN in Beijing Dongzhimen Hospital which was induced by the Hiding Perverse Trend Rationale from Dec.2015 to Jun.2016,including 9 males and 11 females,add up to be 20 cases.The sex ratio indicated to be 1.22:l,the ages range from 18 to 62,the average age is 41.32±10.56.We took down the initial condition of all the patients and the condition after a particular period with the medical treatment formula,then comparied and marked them into three groups:the basic group(initial condition),the formula I group(After 3 months)and the formula II group(After 6 months).There is no statistical difference between the three groups during the particular period.Thus we mainly observed and assessed such indexes as syndromes,24hUTP,Scr,eGFR,the secondary index-es are BUN,ALB,PRO,BLD.We drawed up an unified traditional clinical syndromes,each par-ticular sign by the Four Traditional Diagnosis and the herbal medicine in Formulae before and after the treatment for 3 months or 6 months.Results:The Hiding Perverse Trend Rationale in possess of a great number of experience via the accumulated fully recovered past cases.In direction of this,it confirms to be effective by observation during this period.i The symptom scores and curative effectAfter the treatment for 3 months,the improved symptom scores show statistical differences(P<0.01)by observation and analysis.The simple symptom such as edema,lumbago,fatigue has lysis in a middle scale.It was of great value in curative effect and statistics.After the six months of follow-up visits,both the symptom and curative effect have an obvious im-provement compared with the initial condition.Even some of the symptom such as the pharynx ache has disappeared and some released.ii Physicochemical indexesAfter three months of treatment,the mainly indexes(24hUTP,Scr,eGFR)significantly declined and showed statistical differences(P<0.05)in compared with the initial condition.Meanwhile,the secondary indexes partly improved.It had no significant statistical differences in analysis.After six months of treatment,the mainly indexes make a further sustained decrease and show sta-tistical differences(P<0.05)in compared with the initial condition.As the same time,the second-ary indexes come down in a definited degree and have verified statistical differences(P>0.05).iii Safety AssessmentCompared with the initial condition,there is no obvious abnormality variety in liver function,blood routines,ECG and BP.Although some patients have slightly problem with blood routines and ECG before the treamtent,it has not aggravated and released on contrary which means the Hiding Perverse Trend Rationale applying to clinical formula is safe and has no obvious side effect.Conclusion:The application of the Hiding Perverse Trend Rationale in the diagnosis of IgAN prove to be effective and safe by observation and analysis,especially for symptoms such as the pharynx ache and the mainly indexes.It has comfirmed to eliminate albumin.Final-ly,this ingenious formula treamtent is safe and has no obvious side effect.It claims to have the characteristic and valuable foreground/prospects in researching and application. |
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