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Analysis Of Blood Glucose Detection Based On Near Infrared Spectroscopy

Posted on:2018-08-30Degree:MasterType:Thesis
Country:ChinaCandidate:X X LiuFull Text:PDF
GTID:2348330518496221Subject:Information and Communication Engineering
Abstract/Summary:PDF Full Text Request
With the advancement of science and technology, people's living standards continue to improve. The incidence of diabetes increased year by year. At present, the medical profession has not been able to find ways to cure diabetes. In the process of observation and treatment of illness,patients are under great pressure with physical and mental brought by frequent blood samples collection. Therefore, non-invasive blood glucose detection recebied the medical profession and the scientific community's attention in recent years. Non-invasive blood glucose detection not only reduce the pain of the majority of diabetic patients in the medical process,but also along with the huge economic benefits in the medical market. It can be said, non-invasive blood glucose detection is of great significance for the people's benefit and prmotion of the country's soft power.On the other hand, near infrared spectroscopy (NIRS), as a green and harmless technique for rapid analysis and measurement, has received much attention from researchers since the 1950s. NIRS was first applied to the analysis of agricultural and sideline products. However, NIR technique has been stagnant because of its low sensitivity and poor anti-interference.With the development of computer technology and chemometrics, the shortcomings of NIRS are compensated. Along with the development of computer technology and chemometrics and the appearance of digital spectrometer, modern spectroscopy has formed a new feature. At present,NIRS has been widely used in industry, agriculture, medicine, chemical and other fields. It provides an important reference for the study of non-invasive blood glucose parameters based on NIRS.Based on the principle and characteristics of NIRS, this paper aims to study a noninvasive blood glucose detection method based on pulse wave signal acquisition system. The work is divided into the following two parts.1. A pulse wave acquisition system based on photoelectric volume method was set up.According to the characteristics of human blood, and the study of the basic knowledge of NIRS, we selected the suitable near infrared light band for human blood glucose detection. According to the theory of photoelectric volume method, a pulse wave signal acquisition system based on transmission method and reflection method are set up by studying the principle of pulse wave in human blood circulation. Through the analysis of the collected pulse wave signal comparison, Transmission acquisition system is selected for this subject experiment.2. Data collection and analysis of blood pressure, heart rate and blood glucose data.Through the comparison of different multiple linear regression analysis, we choose partial least squares method to analyze data, and program the partial least square algorithm procedure through MATLAB. In order to collect the characteristic parameters of pulse wave, blood pressure,heart rate and blood glucose data, the sample data is collected through experiment. The collected signals are analyzed by scatter plot method,correlation analysis method and partial least squares regression model. The relationship between the characteristic parameters of pulse wave, blood pressure, heart rate and blood glucose parameters and the regression equation are obtained.In this paper, through a variety of parameters and blood sugar between the data analysis, non-invasive blood glucose detection are studied.Although there are large differences between individual data, the experimental data affected by the larger environment, such as the lack of samples of regret in this subject, Although this subject there are large differences between individual data, the experimental data affected by the larger environment, such as the lack of samples of regret. We provides a possible reference direction for future non-invasive blood glucose research combined with the characteristics of pulse wave parameters, heart rate,blood pressure and other physiological parameters of the blood glucose parameters.
Keywords/Search Tags:Near Infrared Spectroscopy, Noninvasive Blood Glucose Detection, Pulse Wave Photoplethysmometry, Correlation Analysis, Partial Least Squares Method
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