Research On The Fast Photoacoustic Tomography Imaging System And Reconstruction Algorithm

Photoacoustic imaging is a nondestructive medical imaging technology developed rapidly in recent years.For medical imaging,it is mainly based on the principle of photoacoustic effect produced by the biological tissue light absortion and the different locations of the organization with different light absorption coefficient.In this paper,the background and application value of photoacoustic imaging are introduced,we study its working principle and process and briefly introduce the photoacoustic equipment developed by the former research group.On this basis,a new fast photoacoustic tomography system is designed and implemented,which includes pulse lasers,high sensitivity ultrasonic transducers,optical path devices,signal preprocessing systems,data acquisition systems and auxiliary mechanical frames.Compared with the original equipment,the new imaging system has greatly improved in the quality of imaging and imaging speed.Secondly,in order to solve how to keep the fine structure details and edge information in the imaging image,a photoacoustic imaging algorithm based on the optimal transfer algorithm and the smoothing regularity is proposed.It can suppress the generation of noise in a certain extent and effectively improve the quality of imaging.Finally,the new fast photoacoustic tomography system is verified by the phantom and vivo experiment,and obtains the ideal imaging quality using the proposed photoacoustic imaging algorithm.The experiment validates that the imaging system can be applied to the study of photoacoustic imaging in vivo.In addition,since a tunable pulse laser is utilizaed during the design of the fast photoacoustic tomography system,so that it has a multi-spectral separation imaging function,which can further improve scientific research and application value of the system.