Clinincal Study On The Treatment Of Children With Cold(Deficiency Of Qi And Wind Heat Syndrome)with Fuganlin Oral Liquid

Objective To investigate the clinical efficacy and safety of fevinoline oral liquid in treating children's cold(Qi deficiency wind heat syndrome)and provide a reliable basis for treating children's cold(Qi deficiency wind heat syndrome).Method The clinical study selected 30 patients who were diagnosed with infantile cold(Qi deficiency and wind fever syndrome)from October 2014 to December 2015 to be treated with Flavorosacrone,take medicine:6 months-1years,5ml each time,3 times perday;1-3 years,10 ml/times,3 times perday;4-6years old,10 ml each time,4 times perday;7-12 years old,10 ml each time,5times one day.The treatment is up to 1 week,within 1 week cure person is stopped at any time.Collect the basic information of the children,observe and record the changes in body temperature before and after taking the medicine,and statistically analyze the antipyretic effect time and the total antipyretic rate,so as to judge the antipyretic effect of the treatment of acute upper respiratory tract infection(air deficiency wind heat syndrome)in children.;Record the changes in the scores and total syndromes of other minor symptoms such as fever, sweating,cough,sore throat,nasal congestion,turbidity,poor feeding,and less facial color before and after treatment,and evaluate the effect of the symptoms;Record the effect of single symptom disappearance rate to determine the clinical single symptom treatment.Observe and record the body temperature,respiration,heart rate,blood pressure,twelve conventional electrocardiograms,three routine,liver and kidney functions,and clinical adverse reactions that occur before and after taking the drug to evaluate the safety of the children.Result 1.Effect of disease: Through the clinical observation of 30 children with acute upper sensation(Qi deficiency and wind heat syndrome),13 children were cured,11 children were shown to be effective,4 children were effective,2 were invalid,the total effective rate was 93.33 %.2.Effect of syndrome:The statistical analysis of the main symptoms and sub syndrome branches before and after treatment showed that the scores of two main symptoms of fever and sweat after the medication were lower than that before the drug use,and the difference was statistically significant(P<0.05).It showed that the oral liquid could effectively relieve the symptoms of fever and sweat caused by acute upper respiratory infection(Qi deficiency and wind heat syndrome)in children.The scores of hypopharyngeal swelling and pain,cough,nasal congestion,muddy DDT,and poor intake were all significantly different compared with those before the medication,and the difference was statistically significant(P<0.05),indicating the symptoms of swallowing red swelling and pain,cough,poor feeding,nasal congestion and DDT in children with acute upper respiratory infection(Qi deficiency and wind heat syndrome).There was also a good clinical therapeutic effect;however,there was no significant difference in the incidence of secondary symptoms,less air and facial Huang Shaohua scores than before medication(P>0.05).3.The effect of the related observation index: from the observation of the time of antipyretic effect,the antipyretic effect was obvious more than 1-2 hours after oral medicine,and the total antipyretic rate of 4 hours and 8 hours was 65.3% and 26.9%,respectively.4.Safety analysis:During the trial,The three major routine,electrocardiogram,liver and kidney function of the children before and after taking medicine were not abnormal,and all the children had no adverse events such as abdominal pain,diarrhea and drug allergy during the period of the trial.Conclusion In the clinical treatment of children with acute upper respiratory tract infection(Qi deficiency and wind heat syndrome),using orally administered orally for the longest 1 weeks,the results of the test showed that the oral liquid was significantly relieved of fever,sweat,cough,swelling and pain of pharynx red,nasal congestion,DDT,poor intake of food and other clinical symptoms,and did not appear.The clinical adverse events such as abdominal pain,diarrhoea and drug allergy have definite therapeutic effect and significant safety.It is worth further research and clinical application.