Professor Shi Liqing's Experience In Treating Chronic Cough And Data Mining Research

BACKGROUND:Chronic cough is a common disease in respiratory clinics.Many patients are diagnosed with long-term untreated cough.After repeated examinations and treatment,they cannot be diagnosed and effectively treated,which seriously affects the quality of life of patients.Professor Shi Liqing has conducted clinical and experimental studies of chronic cough for more than 20 years,has accumulated rich experience and recorded a large number of medical records.This study will discuss and summarize the clinical experience of tutors in the treatment of chronic cough,and use cluster analysis methods to study the tutor's medical record,induction tutors treatment of chronic cough syndrome differentiation,medication law,in order to better guide the clinical and improve efficacy.The first part of this study reviewed ancient physicians' understanding of chronic cough and the experience of traditional Chinese medicine in the treatment of chronic cough.Secondly,the research progress of modern medicine on the etiology,pathogenesis,diagnosis and treatment of chronic cough is summarized.The second part of this study is Professor Shi Liqing's experience in treating chronic cough.Objective:To study the chronic cough caused by the tutor for more than 20 years,to sum up the understanding of the tutor on the etiology and pathogenesis of chronic cough,main classification,syndrome differentiation and treatment.Results:The tutor put forward the basic pathogenesis of chronic cough caused by wind evil and lungs,and combined with the theory of chronic evil to explain chronic cough.The tutor thinks that the chronic cough disease is located in the lung and is related to other organs.The relationship with the spleen is the most important.Closely;Mentor proposed that the common symptoms of chronic cough are wind evil lung,damp heat lung,lung yang deficiency,cold drink lung,dampness lung,lung yin deficiency;tutor in the diagnosis and treatment process pays attention,treatment Use multiple methods and use light medicine.The third part of this study is data mining research.OBJECTIVE:To use data mining techniques to summarize Professor Shi Liqing's treatment of chronic cough.PARTICIPANTS:The medical records of patients with chronic cough who were admitted to the Department of Respiratory Diseases of the Dongfang Hospital of Beijing University of Chinese Medicine from February 2009 to December 2017 were screened for 660 medical records meeting the requirements.Method:Establish a database and clean the data.Descriptive statistics and analysis of the characteristics of chemotherapeutic agents used to treat chronic cough with the Apriori association rule.Results:1 Gender and age of the patients:Female patients accounted for 67.58%,male patients accounted for 32.42%;young and middle-aged were young people,young patients accounted for 36.21%,middle-aged patients accounted for 33.94%,and the ratio of boys and girls was similar in young patients;cough accompanied by symptoms are more common in Female patient.2 Course of disease:The course of the disease varies greatly,with a minimum duration of 2 months,a maximum duration of 50 years,and a median duration of 24 months.3 Coughing time:67%of patients with coughing both day and night,including 70%of patients with nighttime aggravation.4 cough season:the highest proportion of winter weight loss accounted for 66%,accounting for 20%in the fall,accounting for 15.8%in spring and 10.6%in summer.5 cough inducement:mainly cold wind(53.94%),odor(47.88%),throat itch(43.18%).6 Complications:Of the 660 cases,cough was urinary incontinence 57 times,cough vomiting 47 times,most of the above two symptoms appeared,cough urinary incontinence patients were female,45 cases of cough vomiting patients were female.7 Tongue images:Tongue red(48.03%),pale red tongue(29.39%),sharp red tongue(8.03%),and red tip(7.88%)appeared more frequently;yellow moss covered 55.45%and white moss accounted for 36.21.%;There are more thin(55.76%),thick(39.39%)and thick(10.61%)mosses.8 symptoms:throat itching(63.94%),odor induced cough(54.39%),cold wind induced cough(47.88%),dry mouth(46.21%),sputum less(41.97%),sputum white(36.21%),cough(34.24%)was the highest frequency.9 Drug distribution:There were 158 prescription drugs in the Chinese Communist Party,63 of which had frequency of more than 20 times,Radix Ephedrae(85.76%),Astragalus membranaceus(82.58%),Lisu Ziyuan(81.67%),Coptis chinensis(78.64%),Pinellia sinensis(76.97%),Paniculaceae(76.06%),Magnolia officinalis(71.82%),Peucedani Radix(71.06%)were the highest;among the drugs with frequencies above 20,31 were warm and 30 cold,and the other was flat.Drugs 5 flavors,5351 times appeared in warm drugs,3987 times in cold and cool drugs,and 464 times in plain drugs.The efficacy of drugs was mainly wind,heat,dampness,dampness,nourishing yin,and phlegm.10 dialectical classification:660 patients dialectical classification,with wind evil lung syndrome,damp heat lung syndrome,lung yang deficiency syndrome,cold drink lung syndrome,lung dampness obstruct lung syndrome,lung yin deficiency syndrome is the most common.11 Analysis of Drug Association Rules:The main drugs of wind lurking in lung include:Radix Ephedrae,Astragalus membranaceus,Magnolia officinalis,Peucedanum sinensis,Amaranthus spp.The main drugs of dampness and heat-suppressing lung syndrome include:Astragalus membranaceus,Peilan,Castor-saffron,raw Coix seed.White-bean pod,Magnolia officinalis,bamboo leaf,Coptis chinensis,Pinellia sinensis,Lisu Ziyuan;The main drugs for the deficiency of the lung yang include:Castor-Mahuang,Poria,Atractylodes macrocephala,Aidonghua,Guizhi;The main drugs of cold drink v lung syndrome are:Guizhi,Poria,Atractylodes Rhizome,Coptis Rhizome,Poria Aster,Qing Xia,and Ephedra;The main drugs for phlegm-inhibiting and lung-inhibiting lung syndrome include:Coptis chinensis,Astragalus spp.,Pinellia temate,fried mustard seed,fried radish seed,radix scutellariae,castor huang,Perrin,Amaranthus persicae;The main drugs of lung yin deficiency syndrome include:Castor-flower yellow,Peucedanum praecox,Ophiopogon japonicus,Astragalus sempervirens,Ape winter flower,Poria pygmaea,and bamboo leaves.Conclusion:The most commonly used syndromes in the treatment of chronic cough in the tutor are wind evil lung syndrome,dampness and heat lung syndrome,lung yang deficiency syndrome,cold drink and lung syndrome,stagnation dampness lung syndrome,lung yin deficiency syndrome.Most of the symptoms of the lung and spleen were found with wind-fighting lungs.In the treatment of drugs,the tutor applies different methods according to different syndromes,Feng Xifu Fu lung syndrome to expelling wind Xuanfei;damp heat Yu lung syndrome to light Xuan lung fistula,heat and dampness;lung yang deficiency syndrome to warm Yang Jianpi,Shufengxuanfei;cold drink to lung syndrome to Wenyanghuayin,Xuanfengxuanfei;dampness block lung to Xuanfei cough,dampness and phlegm;lung yin deficiency syndrome to Yangyin heat,lungs and cough.At the same time as the card treatment,according to the basic pathogenesis of chronic coughing wind evil lung and spleen related characteristics,commonly used hurricanes and lung and spleen drugs.