| Objective:To investigate the prevalence of cognitive impairment and its related factors in the population over 65 years old,and provide reference for the prevention and treatment of the disease.Methods:10 Street in Mawei District Luoxing village over the age of 65 elderly population prevalence of cognitive impairment,including 556 males and 477 females.Retrospective analysis of the medical data,including gender,age,BIM,blood pressure,past history(hypertension or diabetes mellitus),blood lipid,blood glucose,liver and kidney function,blood cells,and the TCM Constitution identification,analysis of TCM Constitution of patients with cognitive impairment.According to the diagnostic criteria of cognitive impairment,SPSS 18.0 statistical software was used to analyze the preval-ence,risk factors and TCM Constitution of cognitive impairment.Results:1.According to the diagnostic criteria for cognitive impairment,134 of these patients were diagnosed with cognitive impairment,the prevalence rate was 12.97%,including 56 males and 78 females.The ratio of male to female was 1.0:1.39,and the prevalence rates were 10.07%and 16.35%.The difference between the two groups was statistically significant(X2=8.970,P=0.003).From each age group prevalence rate comparison,more than 85 years old had the highest rate,80-84 years old is less,the prevalence rates of each age group were significantly different(Z=17.767,P=0.001).The prevalence of illit-eracy was highest among illiterates,and the prevalence rate was lowest among universi-ties.The prevalence of different educational levels was significantly different(Z=-6.432,P=0.000).2.Whether exercise showed significant statistical significance in the presence of cognit-ive impairment(Z=2.677,P=0.007).3.The scores of systolic and diastolic blood pressure in cognitive impairment group w-ere higher than those without cognitive impairment,the difference was statistically sign-ificant(P<0.05).4.The BaPWV of cognitive impairment patients is higher than that of the patients with out cognitive impairment,but the difference between the two groups was not statistical-ly significant(PL=0.042,PR=0.444).Whether lower extremity atherosclerosis(Z=2.212,P=0.027)showed cognitive impairment was statistically significant.5.The ALT and albumin values of cognitive impairment patients were lower than those without cognitive impairment,Transaminase ratio and LDH were higher than those with out cognitive impairment,the difference was statistically significant(P<0.05).6.RBC,Hb and HCT in cognitive impairment were lower than those in non cognitive impairment patients,there was a significant difference between the two groups(P<0.05).7.The constitution of Chinese medicine,the investigation of the crowd to clamp the main body,the individual can appear more than one kind of physical type.Only a sim-ple flat quality of 194 people(18.8%),biased constitution for the people(81.2%).The pr-oportion of yin deficiency was the highest,53.5%,followed by phlegm dampness,acco unting for about 51%,the lowest specific quality,was about 4.7%,and the quality of qi stagnation was about 8.4%.In patients with cognitive impairment,yin deficiency and phlegm dampness are the main ones.Patients with Yin deficiency may be more likely to suffer from cognitive impairment(P=0.093).8.Spearman correlation analysis showed that gender was negatively related to orientati-on,attention and computational power,language ability and MMSE score;Educational level was positively related to orientation,memory,attention and computational power,recall ability,language ability and MMSE score;Exercise was positively related to me mory and orientation,and BaPWV was positively related to MMSE scores;RBC,Hb,and HCT were positively related to orientation,attention and computational power,la-nguage ability,and MMSE scores;The quality of the Pinghe and the deficiency of Qi are positively correlated with the directional force;Blood stasis was negatively correlat-ed with directional force and total MMSE score;The quality of qi depression is negati vely related to memory.9.Multivariate logistics regression analysis showed that,age(P=0.000,OR=:1.440,95%CI:1?205-1.720),gender(P=0.003,ORF=1.745,95%CI:1.208-2.521),LDH(P=0.014,OR=1.006,95%CI:1.001-1.011),transaminase(P=0.020,OR=1.727,95%CI:1.089-2.738)is the risk factors of cognitive impairment;Culture(P=0.000,OR=0.515,95%CI:0.421-0.630),the degree of movement(P=0.002,OR=0.680,95%CI:0.530-0.873),albumin(P=0.006,OR=0.904,95%CI:0.841-0.971),RBC(P=0.004,OR=0.532,95%CI:0.345-0.820),Hb(P=0.004,OR=0.980,95%CI:0.967-0.994),HCT(P=0.007,OR=0.001,95%CI:0.000-0.148)is a prote-ctive factor for cognitive impairment.Yin deficiency(P=0.087,OR=1.203,95%CI:0.973-1.488),blood stasis(P=0.065,OR=1.291,95%CI:0.984-1.694),qi depression(P=0.093,OR=1.368,95%CI:0.949-1.972)may be the risk factors of cognitive impairment.Conclusion:1.This study found that the prevalence of cognitive impairment was 12.97%in people over 65 years old,The prevalence rate of female was higher than that of male,and the influence of gender on cognitive impairment was further studied after exclusion of confounding factors such as education level.Age is a risk factor for cognitive impairm ent.The higher the age,the greater the likelihood of cognitive impairment.The educat-ional level is the protective factor,and the higher the educational level,the lower the possibility of cognitive impairment.2.The influence of hypertension and diabetes on cognitive impairment is not significant,but the blood pressure and blood sugar of cognitive impairment patients are higher than that of normal elderly people.Anemia is a risk factor for cognitive impairment.3.The levels of albumin,TB and DB in patients with cognitive impairment were lower than those without cognitive impairment,The change of serum bilirubin may be of some significance in the early diagnosis of cognitive impairment.The ALT of cognitive impairment patients is lower than that of patients without cognitive disorder,and the aminotransferase ratio is higher than that without cognitive impairment.4.Yin deficiency,blood stasis and qi depression may be more susceptible to cognitive impairment. |
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