| ObjectiveTo observe the clinical effectiveness and safety of toric orthokeratology lens.MethodsWe selected 120 patients without other organic diseases of the eye.The sample ages range from 8 to 18 years old,all with myopic astigmatism,myopic degrees between 0.50 and 6.00D,astigmatism between 0.50 and 6.00D,and axial astigmatism at 180±20°.According to the method for correcting refractive errors,they were divided into three groups:40 cases of toric orthokeratology group(experimental group),40 cases of ordinary spectacles group(control group 1)and 40 cases of ordinary orthokeratology group(control group 2).Collecting the data of the central corneal thickness at the time of being wearing the lens,1-week,1-month,3-month,6-month,9-month,and 1-year in the experimental group and control group 2 were followed.Collecting the data of the corneal endothelium at the time of being wearing the lens,1-month,3-month,6-month,9-month,and 1-year in the experimental group and control group 2 were followed.Collecting the data of the breakup time of tear film,corneal spotting,and lens motion at the time of being wearing the lens,1-day,1-week,1-month,3-month,6-month,9-month,and 1-year in the experimental group and control group 2 were followed.Collecting the data of the uncorrected visual acuity at the time of being wearing the lens,1-day,1-week,1-month,3-month,6-month,9-month,and 1-year in the experimental group was followed.The axial and corneal curvatures of the experimental group and control group 1 before wearing lens,6-month,and 1-year were followed.ResultsUncorrected visual acuity:In the experimental group,the uncorrected visual acuity was 0.783±0.289 before wearing lens,and the uncorrected visual acuity increased to 0.335±0.186 in one day after wearing lens,rose to 0.045±0.085 in one week,and increased to-0.015±0.07 in 1-month,and in 3-month was-0.003±0.069,in 6-month,it was-0.003±0.036,in 9-month it was-0.005±0.032,and in one year it was-0.008±0.027.After wearing lens,the difference was statistically significant between the uncorrected visual acuity and wearing lens.The visual acuity of the control group 1 was 0.715±0.334 before wearing lens,and the visual acuity was0.006±0.020 after 1 year.Between the experimental group and the control group 1,there was no statistical difference in the visual acuity before wearing lens,and there was a statistically significant difference in corrected visual acuity at the time of wearing lens.Axial length:The axial length of the experimental group before wearing lens was 24.93±0.92 mm,the axial length of the lens after wearing lens was 25.01±0.92 mm after 6 months of wear,increased by 0.08±0.05 mm,and the axial length of eyes after wearing lens was 25.06±0.92 mm after 1 year wearing lens,it had an increase of 0.14±0.06 mm.The difference between the wearing of the axial length and the wearing of the lens was statistically significant.The axial length of the control group 1 sample wearing lens was 24.67±0.72 mm.The axial length after wearing the lens was 6 months.24.80±0.72mm,an increase of 0.13±0.07mm,wearing lens one year after the eye axis was 24.87±0.73mm,an increase of0.20±0.09mm.The difference between the wearing of anterior axial length and wearing lens was statistically significant.The equivalent refractive power:The equivalent refractive power after wearing the lens of the experimental group was measured after 2 weeks of wearing a toric orthokeratology lens.The equivalent refractive power of the experimental group before wearing the lens was 3.71±1.56D.One year after wearing the lens,the equivalent refractive power was 3.96±1.60D.There was a statistically significant difference between the equivalent refractive power before wearing lens and that after wearing the lens.The equivalent refractive power of the control group 1 before wearing lens was 4.04±1.80D.One year after wearing lens,the equivalent refractive power was 4.54±1.81D.The difference between the equivalent refractive power before wearing lens and wearing lens was statistically significant.The difference between the equivalent refractive power of the experimental group and the control group 1 before wearing lens and 1 year after wearing lens was different and no statistical significance.In the experimental group,the prefrontal corneal curvature and wearing lens were compared for 6 months.After1 year,the difference was statistically significant.The corneal curvature of the control group 1 wearing lens before and after wearing lens was statistically significant after 6 months.There was no significant difference of corneal curvature before wearing the lens and after 1 year.The central corneal thickness:In the experimental group,there was a statistically significant difference in the central corneal thickness and the wearer's wear after wearing lens.The difference in the central corneal thickness and the wearer's wear before the wearing of the control group was statistically significant.In the experimental group,the number of corneal endothelium counts before and after wearing lens was significantly higher at 1-month,3-month,6-month,9-month,and 1 year.The corneal endothelial cell counts before and after the wearing of the control group were compared.After wearing lens,the difference between 9-month and 1 year was not statistically significant,and the difference between 1-month,3-month,and 6-month was statistically significant.In the experimental group,there was a statistically significant difference between tear time before wearing lens and after wearing lens.There was a statistically significant difference between the tear time of the control group before wearing lens and the time after wearing lens.In the experimental group,the difference of movement between before wearing the lens and after wearing lens was statistically significant in 1-month,3-month,6-month,9-month,and 1 year.The control group 2 samples wearing lens before the lens activity and wearing lens.After the comparison,there were statistically significant differences at 1 week,3 months,6 months,9 months and 1 year.In the experimental group,corneal spotting was observed in 1(2.5%)at 1 week,1(2.5%)at 1 month,3(7.5%)at 3 months,and 2(5%)at 6 months.There were 7 people(17.5%)in the I-staining group,and no II,III,and IV staining.The corneal spotting conditions in the control group were as follows:2(5%)in 1-month and 1 (2.5 in 3-month).%),3(7.5%)in 6-month,5(12.5%)in grade I,1(2.5%)in grade II,and no grade III or IV.There was no significant difference between the experimental group and the control group 2 in the corneal spotting after wearing lens for 1 year,c~2=0.0918,P>0.05.ConclusionsThis study used ordinary orthokeratology lens and frame glasses as references,showing that wearing a toric orthokeratology lens can improve the uncorrected visual acuity of patients after getting off the lens,effectively control the growth of axial length and diopter of the patient,reduce the curvature of the cornea,and there is no serious cornea complications,which have a small effect on corneal thickness and corneal endothelial cell count,may cause breakup time of tear film to decrease,but there is no difference compared with ordinary orthokeratology lens.It is suggested that the fit of toric orthokeratology lens to patients with myopic astigmatism is safe and effective under standard wearing and regular follow-up.This study provides objective clinical data bases for the use of toric orthokeratology lenses. |
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