Based On The Image Thinking Of "Tianlongjie" Regimen For Ipf Different Periods And Treatment Of Comprehensive Efficacy Observation

Objective:This study evaluated the core laboratory indicators(high-resolution CT,pulmonary function),core symptoms of clinical symptoms(difficulty score,cough score),quality of life(St.George's Respiratory Questionnaire),and visual indicators of Yang deficiency(infrared thermal image)in IPF patients.)Methods were used to evaluate the comprehensive curative effect of “Tianlongjie” staging and treatment based on image thinking in the treatment of IPF,in order to provide more clinical evidence for the application of “Tianlongjie” scheme on the basis of previous work,and to explore Yunnan ethnic medicine.New ideas and methods for preventing and controlling IPF in resources.Methods: Randomized parallel controlled trials were conducted and divided into experimental group and positive drug control group with 18 patients in each group.The experimental group was treated with “Tianlongjie”regimen(1 dose per day,divided into 3 doses after meals)."pirfenidone"(according to the instructions to increase the amount to 600 mg Po Tid,),the two groups at the same time taking the corresponding simulation agent,treatment for 3 months,comparing the two groups of patients before and after treatment with high resolution(HRCT),pulmonary function(ventilation and diffusion function),Breathing Difficulty Score(m MRC),Cough Visual Analogue Scale(VAS),St.George's Respiratory Questionnaire(SGRQ),and Infrared Thermal Imaging(TTM)were used to perform statistical analysis to form a comprehensive evaluation system.Result:(1)Pulmonary function test indicators:intra-group comparison,the DLco index of lung function after treatment was significantly different from that before treatment in this group(P<0.05),there was no significant difference between TLC and VC.Before and after treatment with Western medicine group,there was no significant difference in TLC,VC,and DLco in lung function tests.Between groups,there was no significant difference in TLC and VC of lung function texts before and after treatment in the two groups(P>0.05),while the difference in DLco was statistically significant(P<0.05).(2)High-resolution CT:In the Chinese medicine group,2 cases were effective,the stability was 17,and 1 cases were null and void.In the western medicine group,there was 1 case effective,14 cases stable,and 3 cases ineffective.There was no statistical difference in the chest HRCT changes before and after treatment in both groups.(3)Dyspnea score results:After treatment,the Chinese medicine group was markedly effective in 3 cases,effective in 17,and ineffective in 0 cases;in the western medicine group,1 case was markedly effective,13 cases effective,and 4cases ineffective.The curative effect of the two groups after treatment was statistically significant(P<0.05).(4)Visual analog score for cough:Visual analog scores of cough after treatment decreased in both groups,and the difference was statistically significant(P<0.05).Differences in visual analog score between cough before and after treatment in Chinese Herbal Medicine group were significantly different from those in Western medicine group(P<0.05).(5)St.George's Respiratory Questionnaire Points:After treatment in both groups,the total SGRQ scores decreased compared with that before treatment.The differences between the two groups before and after treatment were statistically significant(P<0.05).Western medicine group had no difference before and after treatment.The total score of SGRQ after treatment in Chinese medicine group was significantly higher than that of western medicine group(P<0.05).The difference of total SGRQ scores before and after treatment in the two groups was statistically significant(P<0.05).(6)Infrared thermography: Compared with the intra-group comparison,,there was no difference between the two groups before and after treatment.Between groups,there was a statistically significant difference in the caloric value of the kidney area between the Chinese medicine group and the Western medicine group(P<0.05),and there was no significant difference in caloric value between the head,limbs and lungs.(7)Safety evaluation: Before and after treatment,there was no statistical difference in liver function and renal function in the Chinese medicine group.Conclusion: the treatment of idiopathic pulmonary interstitial fibrosis based on the "Tianlongjie" staging treatment plan based on image thinking can significantly improve the patient's symptoms and signs.It can significantly improve the patient's diffusion function and improve the patient's quality of life.It has a stable effect on lung function indexes and high-resolution CT.There are no obvious toxic side effects and adverse reactions in the course of treatment.It is safe and reliable and worthy of clinical in-depth study.