| BACKGROUND:Gastric cancer is a worldwide epidemic.The standard and definitive treatment for gastric cancer is surgical resection:gastrectomy.Surgery is a common trigger for gastroparesis.DGE is arguably the most common of the post-gastrectomy syndromes,accounting for 5-20%of all cases.A clear etiology still remains unidentified.OBJECTIVE:The aim of the study is to evaluate the incidence and potential risk factors for Delayed Gastric Emptying following Distal Gastrectomy for Gastric Cancer.METHODS:A retrospective study was conducted for patients who underwent distal gastrectomy for gastric cancer from January 2010 to December 2015 in ZhongDa Hospital affiliated to Southeast University.The medical records were obtained and analyzed retrospectively to evaluate potential risk factors for delayed gastric emptying(DGE).Medical data was collected.Patients were divided into two groups-DGE and non-DGE.A comparison study was done with respect to clinico-pathologic features such as age,gender,comorbidity(such as diabetes mellitus,hypertension,cardiac or cerebrovascular ischemic disease),operative conditions,tumor site,TNM stage,anastomosis type,reconstruction method,resection extent.RESULTS:A total of 252 patients who underwent distal Gastrectomy for gastric cancer were reviewed retrospectively.Postoperatively,18 patients developed DGE with an occurrence rate of 7.1%.A comparison between DGE and non-DGE groups revealed significant differences with respect with the following:?gastric outlet obstruction(P= 0.031),?Roux-en-Y reconstruction surgery(P= 0.041),? side to end gastrojejunostomy(P= 0.003),?tumor in the lower 1/3rd(P=0.027)and ?ulcerative lesion(P= 0.001).CONCLUSION:The study revealed several risk factors for DGE after distal gastrectomy for gastric cancer including Roux-en-Y reconstruction,gastric outlet obstruction,tumor of the lower 1/3rd stomach,side to end gastrojejunostomy and presence of ulcerative lesion. |
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