Thoracoscopic Segmentectomy And Lobectomy For The Treatment Of Lung Cancer

Objective:Lung cancer is a malignant tumor with high morbidity and mortality.In the early treatment,thoracoscopic minimally invasive surgery is effective,and thoracoscopic lung resection and lobectomy are more extensive.Two surgical procedures in the treatment of early non-small cell lung cancer in patients with short-term efficacy differences,this study,to explore the thoracoscopic segmentectomy and lobectomy clinical effect.Methods:A total of 127 patients with lung cancer were enrolled in our hospital from January 2014 to December 2016.All patients underwent CT and MRI.The patients were diagnosed as early non-small cell lung cancer by operation and pathology.The study process acquires patient informed consent and is in line with medical ethics.Of these,63 patients underwent thoracoscopic lobectomy.The remaining 64 patients underwent thoracoscopic segmentectomy set as the observation group.The perioperative index,pulmonary function index,postoperative VAS pain score,complication status,quality of life score,postoperative recurrence rate and survival rate were analyzed.Results:(1)Two groups of perioperative indexes were compared: the blood loss(69.7 ± 12.1)ml,the drainage volume(583.4 ± 51.2)ml,the drainage time(3.4 ± 0.8)d,the hospitalization time(9.3 ± 2.6(95 ± 1.1)d,the hospitalization time(13.1 ± 3.7)d,the data were compared,the differences were found in the control group(157.3 ± 30.2)ml,the drainage volume(985.2 ± 151.7)ml,the drainage time(4.5 ± 1.1)(P <0.05);the number of lymph nodes were compared between the two groups,the observation group and the control group showed no significant difference(P > 0.05).(2)Comparison of lung function in the two groups: the percentage of forced vital capacity(FVC%)was(85.3±5.7)% in the observation group,the maximal voluntary ventilation(MVV%)was(81.3±8.3)%,FEV1% was(84.7±5.3)%;FEV1% and MVV% of the control group were(78.1±6.7)% and(75.9±6.7)%,and the percentage of forced vital capacity(FVC%)was(82.7±4.9)%,the difference between the two groups was significant,FEV1% of the observation group was significantly better than the control group,the difference was statistically significant(P <0.05);(3)VAS scores of the two groups were compared: the VAS scores of the observation group were(6.06 ± 0.93)points at 1d,3d and 7d after the operation(3.01 ± 0.51)and(2.01 ± 0.51)points were significantly lower than those in the control group(7.73 ± 1.81),(3.52 ± 0.85)and(2.52 ± 0.98),the difference was significant(P <0.05)(P <0.05).(4)the complication rate between the two groups,the control group although slightly higher than the observation group,but the difference was not statistically significant(P > 0.05)?3 cases of pulmonary leakage in the control group,4 cases of pulmonary atelectasis,1 case of pulmonary infection,2 cases of empyema,4 cases of arrhythmia;1 case of pulmonary leakage in the observation group,2 cases of atelectasis,1 case of empyema,3 cases of arrhythmia.(P> 0.05).(5)The quality of life scores of the two groups were compared: the QOL score of the control group was significantly higher than that of the control group(P <0.05),but there was no significant difference between the two groups(32.31 ± 4.72)points,6 months after QOL score(45.76 ± 6.35)points.The QOL score of the observation group was(33.14 ± 4.76)and the QOL score was(49.14 ± 6.41).There was significant difference between the two groups(P <0.05).(6)There was no recrudescence caes in the tow groups.The survival rate was 98.41% at 6 months postoperatively and 100% in the observation group at 6 months after operation.There was no significant difference in recurrence rate and survival rate between the two groups(P> 0.05).Conclusion:Thoracoscopic segmentectomy and lobectomy are the common surgical methods for the treatment of early non-small cell lung cancer.Both of them can achieve good therapeutic effect.However,in the study,the two clinical trials There are some differences.This study found that: thoracoscopic segmengtectomy than lobectomy perioperative indicators(intraoperative blood loss,drainage,length of stay,drainage time,etc.),lung function indicators,postoperative pain,quality of life Improve the situation and so better,and two surgical treatment after the occurrence of complications,recurrence rate and survival rate was no significant difference.Thus,thoracoscopic segmengtectomy and lobectomy in the treatment of lung cancer patients have a certain feasibility,and segmentectomy of the overall effect is better than lobectomy,has a greater clinical value.