Analysis Of The First CD4~+T Lymphocyte Results Of Newly Confirmed Hiv Cases From 2011 To 2015 In Jilin Province

ObjectiveThrough study the characteristic of newly confirmed HIV cases and analyze the first CD4~+T lymphocyte results from 2011 to 2015 in Jilin province,to understand the epidemiological characteristics and CD4~+T lymphocyte baseline in newly confirmed HIV infection,then provide evidence including early detection and strengthen the follow-up,providing timely antiretroviral therapy,improving the quality of life and extending the survival time of HIV-infected persons.MethodsAcquire AIDS direct reporting case report card in January and annual HIV/AIDS follow-up management database in July from 2012 to 2016 of Jilin province from HIV/AIDS integrated prevention and control information system.so as to select the newly confirmed HIV-infected persons from 2011 to 2015,extracted the related materials of demography and epidemiology and the results of the first CD4~+T lymphocyte test.Use SPSS for the related statistical analysis.Descriptive analysis was used to discuss the epidemiological characteristics and temporal variation trend of the results of the first CD4~+T lymphocyte test for HIV infection and the newly confirmed HIV-infected persons respectively from 2011 to 2015.Enumeration data were described by rate description or constituent ratio,comparison among groups used the chi-square test and the results of the first CD4~+T lymphocyte test used the median[M(P25,P75)].Results1.The analysis of epidemic characteristics of the newly confirmed HIV-infected cases from 2011 to 2015 in Jilin Province showed that the number of newly confirmed HIV-infected persons increased year by year,there was statistical significance in different age of the form among the newly confirmed HIV-infected cases in five years(?~2=52.971,P<0.001).The proportion of newly confirmed infections among<30years old was increasing year by year(?~2=38.575,P<0.001),there was statistical significance in the different marital status constitutes in five years(?~2=24.918,P=0.002).The percentage of HIV-infected persons who are unmarried was increasing annually,there was statistical significance in the professional occupation in five years(?2=83.261,P<0.001).The percentage of HIV-infected persons on housekeeping,housework and unemployment was relatively increasing.There was no statistical significance in gender,ethnic,education in five years(P>0.05).2.The analysis of the infection routes,sample sources and contact history of the newly confirmed HIV-infected persons in this five years showed that there was statistical significance in these different variables(P<0.05).The percentage of HIV-infected men who have sex with men was significantly changed,the percentage of counseling was increasing and the percentage of men who have sex with men was increasing year by year.3.The numbers of newly confirmed HIV-infected persons who had completed the first CD4~+T lymphocyte test was increasing annually;CD4~+T lymphocyte?350/?L group accounted for 35.3%,there was statistical significance in the different year for positive rate of CD4~+T lymphocyte less than or equal to 350/?L(?2=15.878,P=0.003).There was statistical significance In the difference age and marital status for positive rate of CD4~+T lymphocyte?350/?L(?2=24.386,P<0.001;?2=21.625,P<0.001)and there was no statistical significance on gender,national,educational level and occupation(P>0.05).4.The analysis of the change trend of the positive rate of CD4~+T lymphocyte?350/?L from 2011 to 2015 showed that there have incremental trend of the positive rate of CD4~+T lymphocyte?350/?L new confirmed infection in age<30years,male,Ethnic Han,high school or secondary school,divorced or widowed,workers,farmers(Tendency Chi-square Test,P<0.05).Conclusions1.The number of newly confirmed HIV-infected persons presented incremental trend annually,and the percentage of HIV-infected persons have the incremental trendamongage<30yrsgroup,unmarriedandoccupationwith housekeeping,housework and unemployment.It is shown that it should to focus on the HIV/AIDS prevention and treatment of these people.The main route of infection of new HIV infection in our province is men who have sex with men infection.2.The numbers of newly confirmed HIV-infected persons who had completed the first CD4~+T lymphocyte test was increasing annually;CD4~+T lymphocyte?350/?L group accounted for 35.3%in total.There was difference in age and marital status for the positive rate of CD4~+T lymphocyte?350/?L;the positive rate of CD4~+T lymphocyte?350/?L group appeared incremental trend which suggested that certain measurements should be adopted for these people in order to bring into ART.