| Objective To abserve the changes of binocular subfoveal choroidal thickness(SFCT)and foveal temporal 500 ?m and nasal 500 ?m in patients with uvitis in acute period and convalescence phase.To provide a strong basis in diagnosis and assessment.To try finding a new way in the aspects of diagnosis and treatment.Methods From January 2016 to April 2017,52 cases of uvitis patients were continuous collected in Tianjin Eye Hospital.We record the patients disease history and clinical date detail.The patients were checked by enhanced depth imaging domain coherence tomography(EDI-OCT).To measure subfoveal choroidal thickness in acute phase(ASFCT)and foveal temporal 500 ?m choroidal thickness in acute phase(AT500)and foveal nasal 500 ?m choroidal thickness in acute phase(AN500)before treatment.Repeat the measurement after one month treatment with oral corticosteroids in recovery period.30 cases of patients repeat the measure were enrolled as controls at same time.All date were analyzed with SPSS11.5.Spearman correlation is used to analyze all kinds of relationship between the choroidal thicknesses.The difference was considered with significance when p<0.05.Results 52 cases of uveitis patients were collected and the mean age was 41.62±15.13 years.The age of cases ranged from 9 to 75 years.Among the panuveitis there were 9 patients with Vogt-Koyanagi-Harada syndrome(VKH)3 patients with Behcet's disease.There were 1 case of map-like choroidal inflammation and 1 case of retinal inflammation.52 patients involved 81 eyes.Among the panuveitis 4patients involved right eyes,7 patients involved left eye,13 patients involved two eye.Among the posterior uveitis 16 patients involved two eyes,7 patients involved right eyes,5 patients involved left eye.The vision of patients was 0.58±0.33,0.62±0.40 in acute period.The vision in recovery period was 0.75±0.30,0.80±0.23.The intraocular pressure was 13.32±5.75,13.57±4.72 in acute period.The intraocular pressure was 13.90± 3.13,14.49±3.53 in recovery period.There was significant difference between uveitis patients and the control group.There was significant difference between VKH and other uveitis in acute stage.There was no significant difference between VKH and other uveitis in recovery stage.There was no significant difference in choroidal thickness between acute stage and recovery stage in BD.When the only one eye involved in acute and recovery period,there was significant difference in the vision between uveitis eye and normal eye.There was significant difference in choroidal thickness between the control group and the both eyes of uvetis group in acute period.In the uveitis groups,the relationship between the anterior chamber inflammation degree and vitreous body inflammatory reaction;there was no correlation between the degree of vitreous inflammatory and anterior chamber inflammatory and the choroidal thickness;there was a linear correlation between the ASFCT and AT500 AN500 and a linear correlation between the RSFCT and RT500 RN500.Conclusion1.In the uveitis patients,the vision in recovery period were better then the vision of acute period;he vision of normal eyes were better then the vision of uveitis eyes.The inflammation subsided,visual acuity improved gradually.2.The choroidal thickness was no significant difference in uveitis eye and normal eyes.The choroidal thickness of recovery period were thinner the acute phase.With reduced inflammation,choroidal thickness thinning,choroid and sclera boundary gradually clear.3.The choroidal thickness of Vogt-Koyanagi-Harada disease was thickening than the other uveitis patients.4.The choroidal thickness of patients was no significant difference between posterior uveitis and panuveitis.5.The choroidal thickness in the acute stage and the recovery period were thicker than the people of normal control group.6.There was a linear correlation between vitreous inflammatory and anterior chamber inflammatory in uvitis group. |
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