Pingganyixuan Cream Adjuvant Treatment Of Liver Yang Hyperactivity Type Of High Blood Clinical Observation Of Pressure

Objective:To observe the effect of oral Pingganxiaxiao combined with benzamethoxazole tablets on the clinical symptoms and dynamic blood pressure of patients with mild to moderate hypertension,and to further explore the combination of traditional Chinese and western medicine treatment of the disease Efficacy,stability and safety,combined with the prevention and treatment of the disease to provide the relevant clinical basis.Methods:In this study,according to the principle of randomized control,included in mild to moderate hyperactivity of hypertension(systolic blood pressure of not less than 140 mmHg but not higher than 179 mmHg and diastolic blood pressure of not less than 90 mmHg but not higher than 109mmHg)patients with 60 cases,Divided into treatment group and control group,each group of 30 cases.For the two groups of patients,to take a different treatment program,the control group given oral liposulfate L-amlodipine tablets(Shi Huida Pharmaceutical Group(Jilin)Co.,Ltd.,approved the number: Chinese medicine Zhunzi H19991083),usage for 5mg / Daily morning at 7 am fasting oral.The treatment group was given control group oral administration based on the addition of Pingganxiaxiao cream(the cream side of the Second Hospital of Shanxi Medical University Professor Dong Lianling experience side by Ligustrum lucidum 100 g,bamboo Ru 100 g,Ophiopogon japonicus 150 g,Polygonatum 150 g,Wolfberry fruit 150 g,fleecer 120 g,mulberry 120 g,Uncaria 150 g,white peony 100 g,Salvia 120 g,Polygalaceae 100 g,Shichangpu 100 g,Bozi Ren 100 g,American ginseng 100 g,turtle glue 200 g and other components According to the traditional processing of ointment process,by the Shanxi Medical University,the second hospital preparation room developed by the strict standardization and standardization of operation,so as to ensure the quality and efficacy of ointment.)Usage: oral,20 g / times,after meals,morning and evening The patients were divided into two groups.The two groups were treated with two courses.The safety parameters,symptoms and 24-hour ambulatory blood pressure were measured before and after treatment.The general condition,symptoms,three general and liver function and renal function were recorded.SP(a)celabs Medical produced 9027.ABP type 24-hour ambulatory blood pressure recorder(ABPM))monitoring,and the experimental data were sorted and statistical analysis.Results:1.Evaluation of efficacy:(1)The two groups of patients with treatment syndrome scores were reduced,the treatment group from the syndrome point of view the total effective rate was 96%,the control group the total effective rate was 83%.The improvement of symptoms in the treatment group was significantly better than that in the control group.(2)The average blood pressure of the two groups was reduced,the total effective rate of the treatment group was 96%,higher than the control group,indicating that the treatment group than the control group.(3)The two groups were treated with blood pressure variability and circadian rhythm.The percentage of diastolic blood pressure in the treatment group was 41%,which was significantly better than that in the control group.The effect of the treatment group on circadian rhythm of blood pressure was better than that of the control group.2.safety evaluation: the two groups of general physical examination,hematuria will be routine,liver and kidney function before and after treatment difference was not statistically significant(P> 0.05),some patients appear flushing,palpitation and other adverse reactions,but self-recovery without special deal with.Conclusion:1.Pingganxiaxiao combined with benzalkonium sulfonate L-amlodipine tablets in the treatment of hyperlipidemia in patients with hyperlipidemia compared with simple oral benzoic acid L-amlodipine tablets group,antihypertensive effect is more significant,stable,for blood pressure day and night Rhythm of the greater degree of improvement,to a greater extent reduce the risk of cardiovascular and cerebrovascular disease.2.No safety problems such as liver and kidney dysfunction were found during the experiment.