Study On The Characteristics Of Sleep Structure In Patients With Epilepsy At Different Time

Objective:To compare the characteristics of the sleep structure of epilepsy patients at different times during the day.Methods:From March 2016 to December 2016,88 patients with epilepsy in the Department of Neurology,the First Hospital of Shanxi Medical University were enrolled in this study.According to the different seizures time of epilepsy during the day,epilepsy patients were divided into three groups: the night attack group(30 cases of epilepsy only during the nighttime sleep),daytime attack group(30 cases of epilepsy only during daytime awake),and mixed attack group(28 cases of epilepsy patients who had seizures during the nighttime sleep and daytime awake).At the same time,Eighty healthy people(80 cases)with epilepsy were selected healthy people(80 cases)as the control group,in the physical examination department.All groups were in our hospital neurological EEG room polysomnography(PSG).The sleep parameters were analyzed by polysomnography.Firstly,the sleep structure of the epilepsy group and the healthy control group were compared.Then the sleep structure of the three groups of epilepsy patients was further compared with each other.Results:1.Comparison of epilepsy group and healthy control group: the total sleep time was significantly shortened(P <0.05),sleep efficiency was significantly decreased(P <0.05),sleep latency,rapid eye movement sleep(REM)latency were extended(P <0.05),non-rapid eye movement sleep(NREM)stage 1,stage 2 and awake period(all P <0.05)were significantly prolonged,NREM3 + 4 period,REM period was significantly reduced(P <0.05).2.Night attack group compared with daytime attack group: the total sleep time was significantly reduced(P<0.05),sleep efficiency decreased significantly(P<0.05),NREM1 stage,2 stage and awake period were significantly prolonged(P<0.05),NREM3 + 4 period,REM period were significantly reduced(P<0.05),sleep latency and REM latency prolonged(P<0.05).3.Night attack group compared with mixed attack group: sleep latency and REM latency were significantly prolonged(P<0.05),NREM1 stage,2 stage and awake perioda were significantly prolonged(P<0.05),While the total sleep time was significantly reduced(P<0.05),sleep efficiency decreased significantly(P<0.05),NREM 3 + 4 period and REM period were significantly reduced(P<0.05).4.The mixed attack group was compared with the daytime attack group: The total sleep time was significantly reduced(P<0.05),sleep efficiency decreased significantly(P<0.05),NREM1 stage,2stage and awake perioda were significantly prolonged(P<0.05),NREM 3 +4 period and REM period were significantly reduced(P<0.05).While the sleep latency and REM latency were significantly prolonged(P<0.05).Conclusions:1.There was a significant difference in the sleep structure between the epilepsy group and the healthy control group;2.There were significant differences in sleep structure among the three groups of night group,daytime attack group and mixed attack group,and the sleep structure of night attack group changed more.