Study Of Sleep Structure Disorder In Obstructive Sleep Apnea Hypopnea Syndrome

ObjectiveTo study the related factors of sleep structure disorders in patients with obstructive sleep apnea hypopnea syndrome,the polysomnography were used to analysis sleep structure.Methods267patients were enrolled in our study.According to the results of PSG,the subjects were divided into three groups: snoring group(female n = 26,male n =25),mild-moderate OSAHS group(female n = 58,male n = 23),severe OSAHS group(female n = 120,male n = 15).All patients' sex,age,height,weight,body mass index(BMI)BMI,neck circumference,Epworth sleepiness scale(ESS),apnea hypopnea index(AHI),Mean oxygen saturation(MSa O2),Lowest oxygen saturation(LSa O2),Total sleep time(TST),percentage of REM period of total sleep time for R%,percentage of NREM period of total sleep time for N %,(N1 period percentage of total sleep time for N1%,N2 period percentage of total sleep time for N2% and N3 period percentage of total sleep time period for N3%),The number of snores,Total awakenings,Total number of micro awakenings,MAI were recorded.All data were compared in three guoups.Results(1)The snoring group was compared with the OSAHS group,the gender composition was statistically significant(P < 0.01),age was not statistically significant among the three groups.BMI and neck circumference were statistically significant with OSAHS groups(P < 0.05).(2)There were statistically significant differences with AHI,snoring times and LSa O2 among the three groups(P < 0.01);MSa O2 in the severe OSAHS group was significantly lower than the other two groups(P < 0.01).(3)There were no differences in sleep latency and sleep efficiency in the three groups.The total sleep time and the MAI of the severe OSAHS group were significantly higher than other group(P < 0.05).(4)The incidence of sleep structure disorder in the severe OSAHS group was higher than that in the other two groups(P < 0.01),and in severe OSAHS group,the N1% and N2% were increased,but N3% and REM% were lower than the other two groups(P < 0.05).(5)Linear regression analysis showed that the disturbance of sleep structure was related to AHI and MAI.Conclusion(1)There were sleep structure disorders in patients with OSAHS,which showed that deep sleep ratio decreased,light sleep ratio and MAI increased and the structure of sleep disorder was particularly obvious on severe OSAHS patients.(2)Respiratory events and microarousal were the cause of sleep structure disorder in patients with OSAHS.