Percutaneous Vertebroplasty And Kyphoplasty For Spinal Tumors: Comparison Of Effectiveness

Objective :To evaluate the safety and effectiveness of percutaneous vertebroplasty and percutaneous kyphoplasty for the treatment of cancerrelated vertebral compression fractures.Methods: Thirty-nine consecutive patients between May 2011 and May 2016,contributing77 cancer-related vertebral compression fractures,were included in the analysis;25 patients(44fractures)were treated by percutaneous kyphoplasty and 14(33 fractures)by vertebroplasty.Pain(visual analogue scale)and function(Oswestry Disability Index)were evaluated pre-and post-operatively,and at 3,6,and 12 months after surgery.The Cobb angle of kyphotic deformity and the height of vertebral bodies were measured pre-and post-operatively.Result: Among the 39 patients,38(97.44%)exhibited significant improvement in pain immediately after surgery,with only one patient reporting an increase in pain.The decrease in pain was comparable between the two groups(P >0.05).Function also improved to the same extent in both groups after surgery.The incidence rate of cement leakage was higher in the vertebroplasty group(42.42%,14/33 vertebrae)than in the kyphoplasty group(27.27%,12/44 vertebrae;P <0.05).No patient reported symptoms associated with leakage.The cost utility ratio was lower for vertebroplasty than for kyphoplasty(P = 0.02).The operation cannot prolong the survival time(P=0.48),and There was no difference in survival time between the two groups(P=0.38).Conclusion: Both vertebroplasty and kyphoplasty percutaneous procedures relieved pain and improved quality of life.However,PKP restored the vertebral body height than vertebroplasty,albeit at a higher cost.Survival was not improved by either procedure.