Correlation Analysis Between Obstructive Sleep Apnea-hypopnea Syndrome And Coronary Slow Flow Phenomenon

[Objective] To investigate the relationship between obstructive sleep apnea syndrome and coronary slow flow phenomenon according to patient's general information,blood biochemistry, left anterior descending branch frames count, TIMI of frame counts of LAD,left circumflex branch and right coronary, the corrected mean coronary flow frames by coronary angiography , apnea hypopnea index, the lowest oxygen saturation, and oxygen reduction index.[method] 146 patients with chest pain were involved in the Department of Cardiology of the Second Affiliated Hospital of Kunming medical university from January 2016 to February 2017 . The general information of patients, including sex,age, weight, height, waist circumference, hip circumference, BMI,And serum biochemistry including fasting blood glucose, fasting insulin, homeostasis model insulin resistance index, fibrinogen, Total cholesterol, triglyceride, high density lipoprotein cholesterol, low density lipoprotein cholesterol, platelet, mean platelet volume, C reactive protein were recorded. According to results of Coronary angiography , LAD frames count, LCX frames count, correction LAD frames count, RCA frames count, mean TFC were recorded.According to the results of AHI,ODI, LSP02,evaluated by polysomnography, patients were divided into CSFP Group and non CSFP group.Non CSFP was randomly selected . We compared the incidence of OSAHS between CSFP Group and non CSFP group.then CSFP Group were divided into OSAHS group and non OSAHS group. The mean and standard deviation(x+s) was used in measurement data with normal distribution, and the difference between the two groups were analyzed by t test. chi square test was used to analyze the differences of the enumeration data, such as gender, hypertension, diabetes,smoking in two groups. Univariate and multivariate Logistic regression were used to analyze the risk factors of coronary slow flow?[results]1 .The incidence of OSAHS in the coronary slow flow group was higher than that non coronary slow flow group (45.8%: 14%). 2. LCX frames (30.45±4.92),RCA frames (38.88±2.10),and mean TFC (30.85 ± 1.90) in the OSAHS group were higher than those in non OSAHS group (21.31 ± 2.6, 35.42 ±6.18, 25.15±1.18) (P <0.05). 3 make AHI, LSA02 and ODI as independent variables, mean TFC as the dependent variable, multiple regression analysis showed that AHI (r=0.87, P < 0.01),ODI (r=0.851,P < 0.01) was positively correlated with mean and TFC, LSA02 had negative correlation with mean (r=-0.82 TFC, P < 0.01).[Conclusions] Coronary slow flow phenomenon was positively correlated with AHI and ODI, and negatively correlated with LSA02, and OSAHS promoted the occurrence and development of coronary slow flow phenomenon.