| Objective:At present, the main treatment of breast cancer at home and abroad to surgery mainly to retain the nipple areola of breast cancer modified radical surgery as a surgical procedure for breast surgery, to retain the patient's nipple areola complex,improve the patient's postoperative cosmetic effect,And to create better conditions for postoperative reconstruction of patients, but its safety is controversial, the subject of the main study of several safety-related factors.MethodsThe data of 137 cases of breast cancer patients admitted to the Department of Pathology, including the name, age, sex, and pathological type of breast cancer, were enrolled in the hospital from October 2016 to December 2016, And molecular classification, the first visit when the ultrasound showed the size of the mass distance from the nipple and the distance from the breast surface of the skin, the number of postoperative axillary lymph node infiltration, preoperative clinical staging and postoperative pathological staging Posterior immunohistochemistry and other clinical data. The relative safety factors of modified radical mastectomy for breast cancer with nipple areola were analyzed by statistical methods. All the data were analyzed by Excel and SPSS22.0 software package. The methods included X2 test,and test level a= 0.05.Results1. The age of the nipple-areola complex infiltration in breast cancer patients was mainly between 40-59 years old. 40 to 49 years old breast cancer patients with nipple areola complex infiltration of the composition ratio of 11.6%, 50-59 years old breast cancer patients with nipple areola complex infiltration of the composition ratio of 5.9%?2. In the case, the breast cancer type with the most common type of breast cancer was ductal carcinoma, the ratio was 8.7%, followed by invasive ductal carcinoma, the composition ratio was 7.8%, and the composition ratio of invasive carcinoma was 3.7%.3. In the case of breast cancer, the composition ratio of Lumina type A breast cancer was 16.7%; followed by HER-2 overexpression, the incidence rate was 12.5%.4. The distance of the edge of the tumor to nipple in the 0.0-1.0cm interval of the composition ratio of 10.9% is under the ultrasound, the composition ratio of the 1.0-2.0cm interval is 9.7%, in this subject beyond the distance of the edge of the tumor to the nipple 2.0cm nipple areola complex no infiltration.5. The original mass diameter of 5.0-10.0cm of ratio of the infiltration of the nipple areola was 35.3% under the ultrasound, secondly the diameter of 2.0-5.0cm the ratio of the infiltration of the nipple areola was 2.1%.6. After surgery, the NAC infiltration composition ratio of axillary lymph node-negative is 3.4%: the NAC infiltration composition ratio of the number of positive lymph nodes between 1.0-3.0 is 3.5%; the NAC infiltration composition ratio of the number of positive lymph nodes between 4.0-10.0 is 17.6%; the proportion of the papilla complex infiltrated with the number of positive axillary lymph nodes greater than or equal to 10.0 was 20.0%.Conclusions1. Age between 40-59 years of age, invasive ductal carcinoma and Lumina type A of breast cancer patients with a high risk of NAC;2. Primary tumor diameter greater than 5.0cm, TND less than 2.0cm of breast cancer patients under ultrasound are not suitable for NSM surgery;3. The surgery risk is much bigger in number of axillary lymph nodes greater than 3.0 breast cancer patients;... |
PDF Full Text Request