The Investigation And Analysis Of Middle-Term QOL Of Related-living Kidney Donors

Objective:To investigate and research the quality of life(QOL)in related-living kidney donors after transplantation procedures.And in the aim to help the patients achieving a better QOL with health education and clinical interfere which based on this research.Methods:This study is a cross-sectional,descriptive design.Under the permission of the hospital ethics committee,we choose 30 related-living kidney donors as objects and Chinese general population as control.Each subject was given a structural questionnaire:(1)a self-made questionnaire which gather general information as sex,age,job and so on.(2)Medical Outcomes Study Short Form-36(MOS SF-36),to assess the QOL of subject.Moreover,we living kidney donors were monitored with Scr,blood pressure and urine protein before,7 days,6 months,a year,2 years and 3 years after surgery.Data were analyzed by Statistical Package for the Social Sciences(SPSS 17.0)for Windows software application program.Statistical methods such as t-test were used to deal with data.Results:(1)At 7 days,6 months,a year,2 years and 3 years after surgery,the serum creatinine of related-living kidney donors is increased compared with preoperative serum creatinine,which was statistically significant(P<0.01),but the mid-term serum creatinine value was only slightly higher than the normal value.But no patients had renal insufficiency,and at 3 years after surgery,the donors exper:ienced a decrease of serum creatinine compared with 7 days after surgery,which was statistically significant(P = 0.027<0.05).The mid-term urine protein of related-living kidney donors was negative.The mid-long-term blood pressure of related-living kidney donors showed no difference compared with their blood pressure before surgery(P>0.05).(2)At 6 months after surgery,comparing with the Chinese general population,the related-living kidney donors showed no difference in most QOL domains except BP and MH.BP is lower than the reference general population.And MH score more higher than norm.However,At 3 years after surgery,comparing with the Chinese general population,the related-living kidney donors showed no difference in most QOL domains except MH.And MH score still more higher than norm.(3)At 3 years after surgery,male showed no difference in most QOL domains compared with female in most domains of QOL except PF.Compared with the donors exceed 50 years old,the youngers got better QOL scores in all domain.Conclusion:(1)After living donor kidney transplantation,the serum creatinine of related-living kidney donors increased compared with preoperative serum creatinine,but the mid-term creatinine value was only slightly higher than the normal value;The mid-term urine protein of related-living kidney donors was negative.The mid-term blood pressure of related-living kidney donors showed no difference compared with their blood pressure before surgery(P>0.05);(2)There are no difference in the mid-term quality of life of related-living kidney donor compared with Chinese general population except MH;(3)The mental health score of donor is higher than that of the Chinese general population.