| Objective:To investigate the influence of kidney excision on donor safety in living related donor renal transplantation in Xinjiang region.Methods:Clinical data of 143 cases of living kidney donors during the period from August,2004 and January,2015 in the first affiliated hospital of Xinjiang medical university were retrospectively analyzed.Data on serum creatinine(Scr),glomerular filtration rate(GFR),serum uric acid(UA),and urine microproteins before operation and three days,seven days,one month and three months after operation were collected to evaluate the impact of nephrectomy on early renal function after operation for donators.Full communication was made to know the psychological condition and quality of life in all donors.Results: Before operation and three days,seven days,one month,three months after operation,the average serum creatinine(Scr)level was(64.2±15.7)?(101.8±24.6),(89.3±15.5),(90.3±21.4),(85.7±17.8)umol/L,respectively;The GFR were,(112.3±21.6),(76.8±19.4),(72.1±16.2),(69.5±17.7),(74.6±12.4)ml/min,respectively;All these data above-mentioned fter operation reached statistical significance compared with that before operation(P<0.05).During the follow-up period,the routine life and work was not influence in all donors.Conclusion:Nephreetomy has significant influence on GFR for donors in the early stage after operation.It is worth to evaluate nephrectomy's long-term effect on the renal function of donors in clinical practice.The donors have good quality of life with no renal injury after kidney donation. |
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