Clinical Analysis Of Small For Gestational Age In Late Preterm Infants

Objective: In this study,we analyse the clinical features of SGA infants in LPIs by collecting relavant information in these infants,for example,birth conditions,risk factors in pregnancy and illness after birth.We aim to provide a theoretical basis of clinical intervention and management for LPIs,especially SGA infants among them.Methods: We analyse the hospitalized neonatal medical records of the second affiliated hospital of Kunming Medical University from January 2015 to December 2016.According to the relationship between gestational age and birth weight,the collected newborns are divided into three groups:SGA in LPIs,AGA in LPIs and SGA in FTIs.And we compare birth conditions,risk factors in pregnancy and illness after birth not only between SGA and AGA in LPIs,but also between SGA in LPIs and SGA in FTIs.Results:1.SGA in LPIs have lower birthweight(1763±161g vs 2463±282g),higher proportion of cesarean section(86.7% vs 59.9%),higher demand of breathing support(15% vs 8.3%) and longer hospital stay(13.1±1.6d vs 10.3±1.5d) than AGA in LPIs(P all<0.05).SGA in LPIs have lower birthweight(1763±161g vs 2296±301g) and higher proportion of cesarean section(86.7% vs 37%) than SGA in FTIs(P all<0.05).2.Mothers who give birth to SGA in LPIs have a higher proportion of suffering from HDCP, multiple pregnancy and fetal distress in uterus(respectively 35.2% vs 13.5%,20.8% vs 13.4%,13.9% vs 3.9%) than AGA in LPIs(P all<0.05).Mothers who give birth to SGA in LPIs have a higher proportion of suffering from HDCP,GDM,abnormalities of placenta or umbilical cord and fetal distress in uterus(respectively 35.2% vs 8.9%,6.4% vs 1.4%,15% vs 6.4%,13.3% vs 4.3%,13.9% vs 3.2%) than SGA in FTIs(P all<0.05).3 After birth,SGA in LPIs have a greater possibility suffering from complications like neonatal asphyxia,hypoglycemia and anemia(respectively 12.1% vs 7.4%,30.6% vs 21.9%,50.9% vs 37.9%) than AGA in LPIs(P all<0.05).After birth,SGA in LPIs have a greater possibility suffering from complications like electrolyte disturbances,anemia,gastrointestinal bleeding and apnea(respectively 65.9% vs 29.5%,50.9% vs 37.7%,6.9% vs 2.5%,8.1% vs 3.2%)than SGA in FTIs(P all<0.05).Conclusion:1.The SGA in LPIs has higher incidence rate of postnatal complications than other infants in our research.2.Mothers who suffered hypertensive disorder complicating pregnancy or fetal distress in uterus have a greater possibility of giving birth to the SGA in LPIs.3.So we should strengthen the monitor of risk factors among pregnant women and master the early prevention and treatment of postnatal complications in SGA among LPIs. And then,we may improve the recent and long-term outcomes of them.