Analysis Of Risk Factors Affecting The Short-term Prognosis Of Late Preterm Infants

Objective: To analysis of risk factors affecting the short-term prognosis of late preterm infants(LPI).Methods: Medical records of the late preterm infants in the Children's Hospital of Chongqing Medical University between September 2017 and September 2019 were reviewed.There were 31 patients in the short-term poor prognosis group and another 62 patients were selected as the control group by Propensity Score Matching(PSM)(1:2).The maternal characteristics,perinatal demography,cardiovascular indices and complications were univariate and logistic regression analysed employed to analyse the risk factors related to short-term prognosis of LPI.Resultes: A total of 93 late preterm infants were enrolled.Compared to the good prognosis group,the poor had lower incidence of appropriate for gestational age(AGA)(67.7% vs 88.7%,P=0.022)and higher incidence of neonatal critical illness score(NCIS)within 24 hours of admission ?90(74.2% vs 46.8%,P=0.015),abnormal mean artery pressuer(MAP)(38.7%vs 12.9%,P=0.007),severe pulmonary hypertension(PH)(22.6% vs3.2%,P=0.001),anemia(25.8% vs 3.2%,P=0.002),necrotizing enterocolitis(NEC)(29.0% vs 3.2%,P=0.001)and sepsis(25.8% vs6.5%,P=0.018).The Logistic regression analysis showed that AGA(OR=0.131,95%CI:0.034~0.500,P=0.003)was the protective factor,NCIS within 24 hours of admission ?90(OR=3.657,95%CI:1.079 ~12.518,P=0.037),severe pulmonary hypertension(OR=2.256,95%CI:1.341 ~ 3.794,P=0.002)and anemia of prematurity(OR=10.392,95%CI : 1.866 ~ 57.879,P=0.008)were the risk factors of LPI's prognosis.Conclusion: AGA was a protective factor.NCIS within 24 hours of admission ?90,severe pulmonary hypertension and moderate-severe anemia were found to be associated with an increased risk of LPI's short-term prognosis.