Analysis Of Risk Factors Of Cirrhotic Ascites Accompanied By Spontaneous Bacterial Peritonitis

Objective : To research the multiple risk factors of cirrhotic ascites patients accompanied by spontaneous bacterial peritonitis(SBP): liver cirrhosis(HBV,HBV with alcoholic,alcoholic,HCV,autoimmune,unexplained,schistosomiasis)causes,history of SBP,hepatic encephalopathy,respiratory tract or digestive tract infection,history of diabetes,upper gastrointestinal bleeding,Child Pugh score,system serum albumin(ALB),albumin/globulin ratio,total bilirubin(TBIL),blood sodium(NA),blood Alanine aminotransferease(ALT)and Aspartate aminotransferase(AST),platelet count(PLT),ascites albumin,prothrombin time(PT)and gender,age etc..Analyze the relevance of the risk factors and provide evidence for early clinical diagnosis and prevention.Methods: Research the cases from 2012 to 2014 retrospectively that 184 patients with cirrhotic ascites were diagnosed in Department of GI medicine and Department of infectious diseases from the First Affiliated Hospital of Anhui Medical University,among which 78 cases belonged to SBP,while 106 cases were defined as non-SBP.What's more,having gathered the relevant clinical data,the author researched the factors that might affect the occurrence of SBP,which were divided into two aspects-the analysis of single factors and multi-factors called logistic regression model,the interrelated risk factors could be identified as an independent risk factor.Results: The analysis of single factor showed that there existed six factors,including serum sodium level,Serum total bilirubin level,hepatic encephalopathy,prothrombin time,Child Pugh score system and clinical history of SBP.And Comparing the differences between two groups had statistical significance,Which to take the further steps to analyze logistic regression of meaningful single factor.The result showed that serum sodium level,serum total bilirubin level and clinical history of SBP were the independent risk factors of cirrhosis with ascites accompanied by SBP(P=0.008?0.044?0.032).Conclusions: Serum sodium level,serum total bilirubin level and the history of SBP were the independent risk factors of cirrhosis with ascites accompanied by SBP,the patients with liver cirrhosis and ascites with these high risk factors should be highly vigilant to SBP occurrence.