| Objective:The evaluation and safety of Renshenyangrong Decoction collaborative measures in preventing senile intertrochanteric fracture postoperative delirium through the comparative analysis of the clinical data of elderly patients with femoral intertrochanteric fracture,which providing reference for clinical rational preventive measures.Methods:200 patients were enrolled that according to inclusion criteria.They were randomly divided into 2 groups(100 cases in the experimental group,the control group of 100 cases).The control group taking western medicine prevention and treatment measures(Psychological guidance,pain management,adjustment of perioperative imbalances,treatment of complications,avoid the use of induced delirium drugs,minimally invasive surgery,rehabilitation team intervention,etc.),the experimental group taking Renshenyangrong Decoction of traditional Chinese medicine that basing on the use of Western medicine prevention and treatment measures.Using CAM to determine the incidence and observation method of delirium scale using DRS-98 score(Delirium Rating Scale,DRS-R-98)assessment of the severity of delirium after admission to the hospital the next morning;and after the 1,3,7 morning blood samples were collected for detection of hemoglobin and C reaction protein.EXCEL software was used to collect the data,and then the results were analyzed by statistical software SPSS 20.0.Results:A total of 191 patients were included in the study and the clinical data were collected,the experimental group(n = 95)and the control group(n = 96).1.Postoperative delirium:the overall incidence of delirium of the experimental group were(16/95)16.84%,lower than the control group the incidence of delirium(28/96)29.17%,the difference was statistically significant(P<0.05).The manic type:3 cases of the experimental group,4 cases of the control group;mixed type:4 cases of the experimental group,5 cases of the control group,no significant difference between the two groups(P>0.05);Inhibitory type:9 cases in the experimental group,the control group of 19 cases,with significant difference(P<0.05).2.The disease severity score of delirium severity score:experimental group score(24.56±3.98)were lower than the control group(27.82±3.57),the difference was statistically significant(P<0.05).3.Hemoglobin content:Comparison between groups:In the four time,the hospital the next day,after the 1,3 day(P>0.05),the difference was not statistically significant,seventh days after operation,the experimental group of hemoglobin content was higher than the control group,the difference was statistically significant(P<0.05).The comparison group,two groups of hemoglobin contents existed on the second day after>the first days>the third days after operation,the difference was statistically significant(P<0.05);the content of hemoglobin group after seventh day on the third day after operation,the difference was statistically significant(P<0.05).The mean value of the control group was 7th day after operation,and the mean value was basically the same,and there was no significant difference(P>0.05)between the control group and the control group.4.Serum CRP content(Creactiveprotein.Crp):Between the two groups:in the four time,the hospital the next day,after seventh days of serum CRP levels of two groups had no significant difference(P>0.05);After first,3rd days,the experimental group was lower than the control group,the difference was statistically significant(P<0.05).In groups comparison:The 3rd day after operation was greater than the first day after operation,the 3rd day after operation was greater than the postoperative 7th day,the 1st,3rd days after surgery was greater than the preoperative,the difference was statistically significant.(P<0.05).Conclusion:The method of the Renshenyangrong Decoction and Western medicine collaborative measures were using in the elderly femoral intertrochanteric fractures,which could effectively preventing the occurrence of postoperative delirium and reducing the severity of delirium in patients,were the positive role of the Hemoglobin and C-reactive protein,the effect is more significant than the pure western medicine measures. |
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