The Correlation Between Red Blood Cell Distribution Width And Severity Of Coronary Stenosis During Admission Hospitalization Among Coronary Heart Disease Patients

Objective?To investigate the correlation between red blood cell distribution width(RDW)and severity of coronary stenosis during admission hospitalization among coronary heart disease patients.Methods:By retrospective case analysis,we studied 335 cases in the cardiology department in the First Hospital of Jilin University,who was operated on coronary angiography from January 2016 to April 2016.According to the number of stenosis coronary,the patients were divided into single number group and multiple group.According to SYNTAX results and coronary angiography,we divided the patients into low and middle-risk group and high-risk group.We registered clinical background(such as age,sex,smoking,hypertension,diabetes)and clinical laboratory tests(such as blood count,blood lipid,glucose,serum liver function and creatinine).For the above three division,the difference for clinical characteristics between two groups were analyzed by statistical method.The correlation study between RDW and SYNTAX score was also analyzed.Thestatistical analysis was conducted by using SPSS 23.0 software.Results:1.Of total 335 study cases,230 cases were with multiple number of stenosis coronary and 105 cases were with single number of stenosis coronary.There were significant difference in age and RDW level between two groups(P<0.05)and the age and RDW level of patients with multiple number of stenosis coronary were older than those with single number.There were no significant difference in age,sex,smoking,hypertension,diabetes,and blood count,blood lipid,glucose,serum liver function and creatinine(P>0.05).2.The results of binary logistic regression analysis showed that the possibility of multi-vessel disease in elderly patients with coronary heart disease was 1.026 times higher than that in patients with coronary heart disease(P<0.05).The high RDW level caused the possibility of multi-vessel disease was 1.140 times than in patients with low RDW level(P<0.05).3.Of total 335 study cases,79 cases were middle and high-risk coronary stenosis with SYNTAX score above 23 and 256 cases were low-risk.There were significant differences in hypertension,diabetes,and RDW between low-risk group and middle and high-risk group(P<0.05).The number of hypertension,diabetes patients and RDW level in middle and high-risk group were higher than those in low-risk groups.Therewere no significant differences age,sex,smoking and blood count,blood lipid,glucose,serum liver function and creatinine(P>0.05).4.The binary logistic regression analysis were used to analyze the risk factors of coronary heart disease in patients with coronary heart disease.The results showed that the possibility of coronary artery disease in those patients who has hypertension was 1.795 times than that in patients without hypertension(P<0.05).The incidence of coronary artery disease in patients with diabetes mellitus was 1.937 times higher than that in patients without diabetes mellitus(P<0.05).The high level of RDW will cause severe coronary artery disease for patients with coronary heart disease.The possibility was 1.146 times than that in patients with who has low RDW(P<0.05).5.SYNTAX score had correlation with RDW which coefficient was0.124 and p value is 0.023.Conclusions:1.Higher RDW level and older age are independent risk factor for multiple coronary artery disease in patients with coronary heart disease.2.History of hypertension,history of diabetes,higher RDW level are independent risk factors of severity of coronary for coronary heart disease patients.3.Higher RDW level had correlation with severity of coronary for coronary heart disease patients and could be used as a simple,easyindicator for screening high-risk patients for primary and outpatient doctors.