| objectiveThrough retrospectively analyzed the clinical data of the huge ovarian tumor,to understand the characteristics of the giant ovarian tumor clinical manifestations,morbidity characteristics,pathological characteristics and diagnosis and treatment method,providing guidance for later huge of diagnosis and treatment of ovarian tumor.MehtodsWe Collected 327 patients with ovarian tumors whose maximum diameter was >10 cm treated by gynaecology of the first hospital of Jilin University from January 2014 to December 2015.All patients were performed surgical treatment,histologic examination,and with complete clinical data.Retrospective analysis it,the general data and clinical data using descriptive statistics,mean and standard deviation(rate),the comparison of measurement data using analysis of variance,count data comparison with X2 test,P < 0.05 can be granted as having a statistical significance.Result1?327 patients of giant ovarian tumor aged 9-83,the average age(44.54±16.75).There are 206 patients who more than 40 years,accounting for 63.0% of the total.2? The major clinical manifestations of 327 patients with giant ovarian tumor is abdominal pain,ventosity,touch a abdominal mass,some patients found by physical examination or because of other illnesses.3? 327 patients of giant ovarian tumors with torsion of ovarian tumor 33 cases,6 cases of ruptured ovarian tumors,2 cases of torsion and rupture of ovarian tumor,the incidence of giant ovarian tumor torsion was 10.7%.in There are 24 cases underwent emergency surgery becauseof abdominal pain of 41 patients with complications of giant ovarian tumor.4?220 cases of patients with benign tumor of huge ovarian tumor in327 cases,accounting for 67.3%;77 cases of malignant tumors,accounting for 23.5%;30 cases of borderline tumor,accounting for 9.2%.Histological type: 215 cases of epithelial tumors,accounting for 65.7%;61 cases of germ cell tumor,accounting for 18.7%;25 cases of sex cord stromal tumor,accounting for 7.6%;5 cases of secondary tumors,accounting for 1.5%;4 cases of tumor like lesions,accounting for 1.2%,8cases of pathological type is unknown,accounting for 2.4%.5? The average age distribution of benign tumors and malignant tumors in 327 patients with giant ovarian tumors was statistically different(P<0.05).According to the age 20< years,20-39 years,40-59 years old,above 60 years old group,by statistical analysis,the different nature of ovarian tumors in each age distribution,there were significant differences(P<0.05),the most of four age groups are benign,mainly occurred in the age group of 20-39;malignant tumors and borderline tumors mainly occurred in the age group of 40-59.6?The epithelial tumor,sex cord stromal tumor,germ cell tumors in Four age groups accounted for huge ovarian tumor 92.1%,it is mainly carried on the statistical analysis.The epithelial ovarian tumor is the most common pathological type of huge ovarian tumors,accounting for 71.4%(215/301),including serous and mucinous tumors are the most common,accounting for 73.5%(158/215);followed by germ cell tumors,accounting for 20.3%(61/301),including ovarian teratoma was the most common,accounting for 88.5%(54/61);sex cord stromal tumor is the most rare,accounting for 8.3%(25/301),including follicularmembrane fibroma of the most common,accounting for 68%(17/25).The different histological types of huge ovarian tumors in each age distribution,the difference was statistically significant(P<0.05).Four age groups were mainly epithelial tumors,epithelial tumor occurred mainly in the 40-59 age group;germ cell tumors occurred mainly in the 20-39 age group;sex cord stromal tumor mainly occurs in more than 60 age groups.7?There are 143 patients were postmenopausal of the 327 patients with huge ovarian tumors,accounting for 43.7%,and there are 184 were not postmenopausal,accounting for 56.3%.By statistical analysis,there is no correlation between the incidence of malignant tumor of the 327 cases with huge ovarian tumor and menopausal status.The distribution of histological types of ovarian tumors in postmenopausal women or not with large ovarian tumors is statistically significant(P<0.05).8?The maximum ovarian tumor of 327 cases of patients is reach the diaphragm,down to the pelvic floor,both sides to the posterior axillary line.According to the maximum diameter of the tumor showed the proportion of malignant tumors in the diameter of 10-15 cm was higher in the huge ovarian tumors,accounting for the total number of the cases 74.0%.9?There was no significant difference in the number of pregnancies and the incidence of malignant tumors in 327 patients with huge ovarian tumors,Delivery times,abortion or not and the incidence of malignant tumors are correlated,The incidence rate of malignant in huge ovarian tumors with abortion than those without abortion,birth more than 3 times more than the 2 is low.10?327 cases of patients with giant ovarian tumor epithelial tumor,sex cord stromal tumor and germ cell tumor accounted for 92.0%,so thestatistical analysis,301 cases of ovarian tumor patients and in postmenopausal ovarian tumor histological type distribution,the difference was statistically significant(P<0.05).11?There were no significant differences in the distribution of the patients with different ages and different types of ovary in the residential areas(P > 0.05)?12?The benign tumors in 327 cases of large ovarian tumors were mainly ovarian tumor resection,and the borderline and malignant tumors were mainly divided into two stages.Conclusion1?The clinical manifestations of giant ovarian tumors are lack of specificity,mainly in women over the age of 40,and most of them are benign tumor.2? The main histological types of giant ovarian tumors are epithelial tumors,followed by germ cell tumors and sex cord stromal tumors?The incidence of epithelial tumors is the highest between the ages of 40-59 years,and the incidence of germ cell tumors is the highest among the ages of 20-39,the incidence of sex related stromal tumors is the highest among the 60 year old and over.3? Among the large ovarian tumors,the incidence of malignant tumors is the highest between the ages of 40-59 years.4? The size of giant ovarian tumor is related to the benign and malignant tumor.When the diameter is greater than 10 cm,the malignant proportion of ovarian tumor increases.5? huge ovarian malignant tumor is correlated with the times of childbirth,abortion or not;the incidence of abortion,birth more than 3times decreased the huge ovarian malignant tumor rate. |
PDF Full Text Request