Epidemiological Survey Of Obesity And Analysis Of The Potential Complications Related To Obesity In Primary And Secondary School Students In Tiantai County

Objective: To investigate the prevalence rate and distribution characteristics of obesity among primary and middle school students in Tiantai County,to further analyze the glucose and lipid metabolism of obese primary and middle school students,and to screen for physical measurement indexes of insulin resistance.Methods: At the first stage,cluster sampling method is adopted to carry out height and weight measurement in 15 primary and middle schools of the county.SPSS13.0software is applied to analyze the incidence rate,male and female ratio,age characteristics,urban and rural distribution,etc.of obesity in primary and middle schools of the county.At the second stage,247 student volunteers are recruited to participate in further physical examination.The participating students are divided into overweight,obesity and normal groups and taken with blood samples for tests of fasting insulin,postprandial insulin,ALT,AST,fasting blood glucose,postprandial blood glucose,total cholesterol,triglyceride,uric acid.The relationship between the measurement indexes and the glucose and lipid metabolism is compared to verify the prediction efficiency of the measurement indexes on insulin resistance.Results:Atthe first stage,10595 primary and middle school students of the county are investigated,1243 of whom are overweight(accounting for 11.73%)and 952 of whom are obese(accounting for 8.99%).The prevalence rates of overweight and obesity are significantly higher in boys than in girls but decline gradually with growth of age(15.05%vs8.06%),(10.61%vs7.18%).Particularly,the prevalence rates of overweight and obesity are highest among 7-year-old students,and show a gradual downward trend among students from 7 to 12 years old,and then remain stable after 15 years old.The prevalence rates of overweight and obesity are higher in primary school than in other learning stages and higher in cities than in rural areas.At the second stage,case control study is processed to reveal that there are obvious blood lipid and glucose metabolism disorders,higher proportion of abnormal liver function,and increased risk of cardiovascular and cerebrovascular diseases and diabetes mellitus among obese primary and middle school students.Obese students' BMI,waist circumference,hip circumference,fat rate,diastolic blood pressure,fasting insulin,postprandial insulin,ALT,AST,2-hour postprandial blood glucose,total cholesterol,low density lipoprotein cholesterol,triglyceride,uric acid,etc.are higher than those of overweight and normal groups.Anthropometric parameters such as BMI,hip circumference,waist circumference,waist-to-hip ratio,fat rate,etc.are linearly and positively correlated to insulin resistance.By calculating the area under ROC curve,body mass index,waist-to-hip ratio,waist circumference and fat rate have certain effect on IR prediction.Conclusion: The prevalence rate of obesity among primary and middle school students in the county is lower than that in the domestic first-tier cities but slightly higher than that in moderately developed areas.Further monitoring and prevention is necessary.glucose and lipid metabolism disorders in obese primary and middle school students can predict insulin resistance by measuring anthropometric parameters.