Analysis And Countermeasures Research On Adverse Drug Reaction Of Asthma Drug In Qiqihar From 2012 To 2015

Objective:Analysis the adverse drug reaction of the asthma drug in Qiqihar, investigate the cognition and asthma control test of Drug Reactions(ADR, referred to as Adverse) in outpatient and inpatient asthma patients in a tertiary hospital in Qiqihar, analysis of various adverse reactions caused by asthma in patients with asthma treatment of drugs, improve the degree of attention of doctors, drug administrators, nurses and patients has an adverse reaction to the treatment of asthma drugs, to strictly abide by the principle of the application of clinical medication due to illness and reasonable regimen to ensure drug safety of patients with asthma. Subject and Methods:Research the treatment of asthma drug ADRs and lead to asthma attack ADRs 2012.1.1-2015.12.30 which Qiqihar Medical Device Adverse reaction evaluation center receive through a retrospective way. Sumed up adverse reactions about patient's age, sex, outcome, seasonal distribution, cumulative system or organ and clinical manifestations, drug dosage form and route of administration, drug types and new serious adverse drug reaction occurrence regularity. Questionnaire survey method is used to investigate the degree of adverse reaction and asthma control test in patients with asthma. Results:(1) Long term use of the treatment of asthma drugs prone to adverse reactions. In 331 cases of adverse drug reactions about the asthma, aged 50-69 patients accounted for the higher than other age groups; there are 7 kinds of the treatment of adverse reactions caused by asthma, Theophylline is the largest proportion of adverse reactions. Chinese medicine accounting for second, the third is inhaled corticosteroids. In the pharmaceutical dosage form, the injection is the highest proportion of adverse reactions. In the pharmaceutical dosage form, the injection is the highest proportion of adverse reactions.(2) Asthma occurred in the late spring and early autumn, because of the special environment in Qiqihar asthma and asthma drug adverse reaction often frequently occurring in summer and autumn.(3) There were many system causing ADRs of asthma, most ADRs were induced by digestive.(4) Antibacterial drugs, captopril and aspirin, citicoline injection and dextran injection, Mannatide Injection, Shuxuening injection, Huangqi injection, puerarin injection, Qingkailing injection, Shuanghuanglian injection, Panax notoginseng saporins injection,Nitroglycerin Injection, Lidocaine hydrochloride mucilage(I) can lead to asthma attacks. If the patient has a history of asthma to inform the doctor, you can avoid the occurrence of adverse reactions to a certain extent.(5) About the investigated, accounted for 49.76% of the total number of asthma patients didn't know knowledge of asthma ADR, the impact of education or other factors in 412 patients with asthma. ACT test score of 20 points or more accounted for 24.28% of patients with asthma. There are 39 patients can't correctly use aerosol, 29 cases over 70 years of age accounting for 74.36%. Non first hospitalized asthma of patients 79.83% can complete implementation of doctor's advice, 38.89% for the first time in hospital with asthma patients to complete the implementation of the doctor's advice. Conclusions:Adverse reactions produced by a single drug use were less than the adverse effects produced by the combination. Good communication between doctors and patients can reduce the incidence of adverse drug reactions of asthma drug. To establish and perfect the ADR monitoring system, carry out drug adverse reaction monitoring activities from the basic level to all levels of management control, prevent the occurrence of adverse reaction, implement the control and prevention of adverse drug reactions in the treatment of asthma, in order to ensure the standardized treatment of asthma.